1407183-51-0

Basic information

• Product Name: pyridin-2-yl-((1S,2R,3R,4R)-3-(p-tolyl)bicyclo[2.2.1]hept-5-en-2-yl)methanone
• Synonyms: pyridin-2-yl-((1S,2R,3R,4R)-3-(p-tolyl)bicyclo[2.2.1]hept-5-en-2-yl)methanone
• CAS NO: 1407183-51-0
• Molecular Weight: 289.377
• Mol File: 1407183-51-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: pyridin-2-yl-((1S,2R,3R,4R)-3-(p-tolyl)bicyclo[2.2.1]hept-5-en-2-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: pyridin-2-yl-((1S,2R,3R,4R)-3-(p-tolyl)bicyclo[2.2.1]hept-5-en-2-yl)methanone(1407183-51-0)
• EPA Substance Registry System: pyridin-2-yl-((1S,2R,3R,4R)-3-(p-tolyl)bicyclo[2.2.1]hept-5-en-2-yl)methanone(1407183-51-0)

Safety Data

• Hazardous Substances Data: 1407183-51-0(Hazardous Substances Data)

Upstream product

• 24582-66-9 1-(2-pyridyl)-3-(4-tolyl)propen-1-one 
• 542-92-7 cyclopenta-1,3-diene 
• 16212-59-2 (E)-1-Pyridin-2-yl-3-o-tolyl-propenone 
• 158014-83-6 (E)‐1‐(pyridin‐2‐yl)‐3‐(p‐tolyl)prop‐2‐en‐1‐one 
• 104-87-0 4-methyl-benzaldehyde 
• 1122-62-9 2-acetylpyridine 

Relevant articles and documents

Enantioselective Diels–Alder reactions with left-handed G-quadruplex DNA-based catalysts

Since the discovery of left-handed G-quadruplex (L-G4) structure formed by natural DNA, there has been a growing interest in its potential functions. This study utilised it to catalyse enantioselective Diels-Alder reactions, considering its different opti

N, N ′-Dioxide/nickel(II)-catalyzed asymmetric Diels-Alder reaction of cyclopentadiene with 2,3-dioxopyrrolidines and 2-alkenoyl pyridines

A chiral N,N′-dioxide/Ni(OTf)2 complex-catalyzed asymmetric Diels-Alder reaction of cyclopentadiene with 2,3-dioxopyrrolidines and 2-alkenoyl pyridines has been achieved. The corresponding chiral bridged compounds were obtained in high yields with excellent dr and ee values (up to 97% yield, 95: 5 dr and 97% ee).

An Efficient Cyclic Di-AMP Based Artificial Metalloribozyme for Enantioselective Diels–Alder Reactions

The diverse structures of nucleic acids as scaffolds have brought the significant advancement for DNA-based enantioselective catalysis, yet RNA-based enantioselective catalysis is lacking investigation. Herein, we report a small, natural RNA of cyclic di-AMP (c-di-AMP) and Cu2+ ions assemble into an artificial metalloribozyme (c-di-AMP·Cu2+), that could effectively catalyze the enantioselective Diels–Alder reactions with up to 80 percent ee. The enantioselective catalytic performance of c-di-AMP·Cu2+ has been studied by thorough investigations of different metal cofactors, c-di-AMP/Cu2+ molar ratios, additives, buffers and c-di-AMP analogues. In addition, the assembly of c-di-AMP·Cu2+ gives rise to 300-fold and 5-fold rate acceleration compared to the uncatalyzed reaction and Cu2+ ions, respectively. This work provides a simple and efficient strategy to construct the RNA-based catalysts that would expand the current nucleic acids-based catalysis and might hint the possible catalytic RNA in primordial chemistry.