158014-83-6

Basic information

• Product Name: 2-Propen-1-one, 3-(4-methylphenyl)-1-(2-pyridinyl)-, (2E)-
• CAS NO: 158014-83-6
• Molecular Formula: C15H13NO
• Molecular Weight: 223.274
• Mol File: 158014-83-6.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 3-(4-methylphenyl)-1-(2-pyridinyl)-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 3-(4-methylphenyl)-1-(2-pyridinyl)-, (2E)-(158014-83-6)
• EPA Substance Registry System: 2-Propen-1-one, 3-(4-methylphenyl)-1-(2-pyridinyl)-, (2E)-(158014-83-6)

Safety Data

• Hazardous Substances Data: 158014-83-6(Hazardous Substances Data)

Upstream product

• 1122-62-9 2-acetylpyridine 
• 104-87-0 4-methyl-benzaldehyde 

Downstream Products

• 1318265-76-7 (C₅H₄N)2C₅H₂NC₆H₄CH₂OC₆H₃C₃HO₂CH₃ 
• 89972-78-1 4'-(4-bromomethylphenyl)-2,2':6',2''-terpyridine 
• 1414998-38-1 6,6-dimethyl-2-picolinoyl-3-p-tolyl-6,7-dihydrobenzofuran-4(5H)-one 
• 1407183-51-0 pyridin-2-yl-((1S,2R,3R,4R)-3-(p-tolyl)bicyclo[2.2.1]hept-5-en-2-yl)methanone 

Relevant articles and documents

Large scale synthesis of 4′-(4-bromophenyl)-2,2′:6′,2″-terpyridine and nature of the mysterious green by-product

4′-(4-Bromophenyl)-2,2′:6′,2″-terpyridine (5) was prepared on a large scale (up to 100 g batches) from 2-[3-(4-bromophenyl)-1-oxoprop-2-enyl]pyridine (3a) and N-[2-oxo-2-(2-pyridyl)-ethyl]pyridinium iodide (4). In the presence of substoichiometric amounts

An Efficient Cyclic Di-AMP Based Artificial Metalloribozyme for Enantioselective Diels–Alder Reactions

The diverse structures of nucleic acids as scaffolds have brought the significant advancement for DNA-based enantioselective catalysis, yet RNA-based enantioselective catalysis is lacking investigation. Herein, we report a small, natural RNA of cyclic di-AMP (c-di-AMP) and Cu2+ ions assemble into an artificial metalloribozyme (c-di-AMP·Cu2+), that could effectively catalyze the enantioselective Diels–Alder reactions with up to 80 percent ee. The enantioselective catalytic performance of c-di-AMP·Cu2+ has been studied by thorough investigations of different metal cofactors, c-di-AMP/Cu2+ molar ratios, additives, buffers and c-di-AMP analogues. In addition, the assembly of c-di-AMP·Cu2+ gives rise to 300-fold and 5-fold rate acceleration compared to the uncatalyzed reaction and Cu2+ ions, respectively. This work provides a simple and efficient strategy to construct the RNA-based catalysts that would expand the current nucleic acids-based catalysis and might hint the possible catalytic RNA in primordial chemistry.

N-Heterocyclic carbene-catalyzed diastereoselective synthesis of β-lactone-fused cyclopentanes using homoenolate annulation reaction

NHC-catalyzed annulation of enals with 2-enoylpyridines or 2-enoylpyridine N-oxides leading to the diastereoselective synthesis of β-lactone-fused cyclopentanes is reported. The reaction proceeds via the generation of homoenolate equivalent intermediates and tolerates a broad range of functional groups.