1408445-11-3

Basic information

• Product Name: 4'-chloro-2-iodo-3-phenyl-3'H-spiro[indene-1,1'-isobenzofuran]-3'-one
• Synonyms: 4'-chloro-2-iodo-3-phenyl-3'H-spiro[indene-1,1'-isobenzofuran]-3'-one
• CAS NO: 1408445-11-3
• Molecular Weight: 470.694
• Mol File: 1408445-11-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4'-chloro-2-iodo-3-phenyl-3'H-spiro[indene-1,1'-isobenzofuran]-3'-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-chloro-2-iodo-3-phenyl-3'H-spiro[indene-1,1'-isobenzofuran]-3'-one(1408445-11-3)
• EPA Substance Registry System: 4'-chloro-2-iodo-3-phenyl-3'H-spiro[indene-1,1'-isobenzofuran]-3'-one(1408445-11-3)

Safety Data

• Hazardous Substances Data: 1408445-11-3(Hazardous Substances Data)

Upstream product

• 1408443-24-2 C₁₄H₁₀ClIO₂ 
• 3923-52-2 1,1-diphenyl-2-propyn-1-ol 
• 13420-63-8 2-chloro-6-iodobenzoic acid 
• 1408444-14-3 benzyl 6-chloro-2-(3-hydroxy-3,3-diphenylprop-1-yn-1-yl)benzoate 

Relevant articles and documents

Facile synthesis of 2-iodo-spiro[indene-1,1′-isobenzofuran]-3′- ones via iodine-promoted cascade cyclization

A novel and efficient synthetic approach to substituted 2-iodo-spiro[indene-1,1′-isobenzofuran]-3′-ones has been developed via an iodine-promoted cascade cyclization of 2-(3-hydroxy-3,3-diarylprop-1-yn- 1-yl)benzoates. This sequential cascade process is concisely conducted at room temperature. Subsequent palladium-catalyzed Sonogashira, Suzuki, and Heck reactions of the resulting iodides proceed smoothly in good yields.