1412439-85-0

Basic information

• Product Name: C₂₆H₂₃NO₄Sn
• Synonyms: C₂₆H₂₃NO₄Sn
• CAS NO: 1412439-85-0
• Molecular Weight: 532.183
• Mol File: 1412439-85-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₂₃NO₄Sn(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₂₃NO₄Sn(1412439-85-0)
• EPA Substance Registry System: C₂₆H₂₃NO₄Sn(1412439-85-0)

Safety Data

• Hazardous Substances Data: 1412439-85-0(Hazardous Substances Data)

Upstream product

• 16727-43-8 2,6-dimethoxynicotinic acid 
• 639-58-7 triphenyltin chloride 

Relevant articles and documents

A triphenyltin(IV) nicotinate derivative - Synthesis and toxicity towards different tumour and normal cell lines

[SnPhM3(DMNI)] (1), (2,6-dimethoxynicotinic acid (DMNIH)) was prepared by the reaction of SnPh3Cl with DMNIH. Molecular structure of 1 was determined by X-ray diffraction studies. The cytotoxic activity of 1 was tested against tumour cell lines human cervical adenocarcinoma HeLa, human myelogenous leukemia K562, human malignant melanoma Fem-x and normal immunocompetent cells, non-stimulated peripheral blood mononuclear cells (PBMC-PHA) and with phytohemagglutinin stimulated peripheral blood mononuclear cells (PBMC+PHA) showing a very high antiproliferative activity against tumour cell lines with IC50 values (after 72 h of treatment) in the range of 46-65 nM. This toxicity becomes lower against normal immunocompetent cells (IC50 values in the range of 88-148 nM) indicating some degree of selectivity towards cancer cell lines.