1413921-02-4

Basic information

• Product Name: 2-(2-isopropoxy-4-nitrophenyl)-5-(2-methyl-4-nitrophenyl)furan
• Synonyms: 2-(2-isopropoxy-4-nitrophenyl)-5-(2-methyl-4-nitrophenyl)furan
• CAS NO: 1413921-02-4
• Molecular Weight: 382.373
• Mol File: 1413921-02-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-isopropoxy-4-nitrophenyl)-5-(2-methyl-4-nitrophenyl)furan(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-isopropoxy-4-nitrophenyl)-5-(2-methyl-4-nitrophenyl)furan(1413921-02-4)
• EPA Substance Registry System: 2-(2-isopropoxy-4-nitrophenyl)-5-(2-methyl-4-nitrophenyl)furan(1413921-02-4)

Safety Data

• Hazardous Substances Data: 1413921-02-4(Hazardous Substances Data)

Upstream product

• 883715-40-0 2-(2-methyl-4-nitrophenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane 
• 1413920-98-5 2-bromo-5-(2-isopropoxy-4-nitrophenyl)furan 
• 1413920-99-6 2-(2-isopropoxy-4-nitrophenyl)furan 
• 423165-35-9 1-bromo-2-isopropoxy-4-nitrobenzene 

Downstream Products

• 1413921-06-8 C₂₀H₂₂N₂O₂ 
• 1413921-12-6 C₃₂H₃₀N₆O₂ 

Relevant articles and documents

Antileishmanial bis-arylimidamides: DB766 analogs modified in the linker region and bis-arylimidamide structure-activity relationships

Analogs of the lead antileishmanial bis-arylimidamide DB766 were prepared that possess unsymmetrical substitutions on the diphenylfuran linker, and an additional compound was synthesized that contains isopropoxy groups meta to the central furan. These agents all displayed nanomolar in vitro potency against intracellular Leishmania with selectivity indexes >100 compared to J774 macrophages. While the unsymmetrical analogs were toxic to mice when given ip at 30 mg/kg/day, the compound bearing the meta isopropoxy groups was well tolerated by mice and showed activity in a murine model of visceral leishmaniasis when administered ip at 30 mg/kg/day for five days.