14171-88-1

Basic information

• Product Name: 7-Phenyl-2-heptanone
• Synonyms: 7-Phenyl-2-heptanone
• CAS NO: 14171-88-1
• Molecular Formula: C₁₃H₁₈O
• Molecular Weight: 190.28
• Mol File: 14171-88-1.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-Phenyl-2-heptanone(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Phenyl-2-heptanone(14171-88-1)
• EPA Substance Registry System: 7-Phenyl-2-heptanone(14171-88-1)

Safety Data

• Hazardous Substances Data: 14171-88-1(Hazardous Substances Data)

Upstream product

• 357212-13-6 2-acetyl-6-phenyl-hexanoic acid ethyl ester 
• 637-59-2 1-Bromo-3-phenylpropane 
• 78-94-4 methyl vinyl ketone 
• 106575-53-5 (E)-7-phenyl-3-hepten-2-one 
• 13633-25-5 1-Bromo-4-phenylbutane 
• 16520-62-0 4-Phenyl-1-butyne 
• 1439-36-7 1-triphenylphosphoranylidene-2-propanone 
• 24346-54-1 3-(iodomethyl)pentane 
• 1629-58-9 4-penten-3-one 
• 3360-41-6 4-phenyl-butan-1-ol 
• 67-63-0 isopropyl alcohol 

Downstream Products

• 602330-58-5 2-(1-methyl-6-phenylhexylidene)malononitrile 
• 602330-67-6 2-amino-4-methyl-5-(4-phenylbutyl)-thiophene-3-carbonitrile 
• 57238-66-1 (E)-7-phenylhept-6-en-2-one 
• 328533-86-4 7-azido-7-phenyl-2-heptanone 

Relevant articles and documents

Generation of Alkyl Radicals from 1-Oxidoalkylidenechromium(0) Complexes by Oxidation with Manganese(III) 2-Pyridinecarboxylate and Their Reactions with Olefins

Tetramethylammonium pentacarbonyl(1-oxidoalkylidene)chromium(0) complexes, prepared from the corresponding carbanion and hexacarbonylchromium(0), are oxidized with manganese(III) 2-pyridinecarboxylate to generate carbon-centered radicals which react with various olefins giving the intermolecular addition products.

Borohydride-mediated radical addition reactions of organic iodides to electron-deficient alkenes

Cyanoborohydrides are efficient reagents in the reductive addition reactions of alkyl iodides and electron-deficient olefins. In contrast to using tin reagents, the reaction took place chemoselectively at the carbon-iodine bond but not at the carbon-bromine or carbon-chlorine bond. The reaction system was successfully applied to three-component reactions, including radical carbonylation. The rate constant for the hydrogen abstraction of a primary alkyl radical from tetrabutylammonium cyanoborohydride was estimated to be 4 M-1 s-1 at 25 °C by a kinetic competition method. This value is 3 orders of magnitude smaller than that of tributyltin hydride.

Synthesis and DHFR inhibitory activity of a series of 6-substituted-2,4-diaminothieno[2,3-d]pyrimidines

A series of 6-aralkyl substituted 2,4-diaminothieno[2,3-d]pyrimidines in which the 6-aryl group is separated from the thieno[2,3-d]pyrimidine ring by two to five methylene groups were synthesized and studied as inhibitors of dihydrofolate reductase from Pneumocystis carinii, Toxoplasma gondii, Mycobacterium avium, and rat liver. Compounds in which the thieno[2,3-d]pyrimidine ring is separated from the 6-aryl substituent by three methylene groups were the most potent inhibitors of the series (with IC50 values ranging from 0.24 and 11.0 μM) but those with two methylene groups between the aromatic rings were the most selective agents.