1417531-46-4

Basic information

• Product Name: 1-((5-((diethylamino)methyl)-4-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)isoxazol-3-yl)methyl)-2-(4-fluorobenzylthio)-6,7-dihydro-1H-cyclopenta[d]pyrimidin-4(5H)-one
• Synonyms: 1-((5-((diethylamino)methyl)-4-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)isoxazol-3-yl)methyl)-2-(4-fluorobenzylthio)-6,7-dihydro-1H-cyclopenta[d]pyrimidin-4(5H)-one
• CAS NO: 1417531-46-4
• Molecular Weight: 676.778
• Mol File: 1417531-46-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-((5-((diethylamino)methyl)-4-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)isoxazol-3-yl)methyl)-2-(4-fluorobenzylthio)-6,7-dihydro-1H-cyclopenta[d]pyrimidin-4(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-((5-((diethylamino)methyl)-4-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)isoxazol-3-yl)methyl)-2-(4-fluorobenzylthio)-6,7-dihydro-1H-cyclopenta[d]pyrimidin-4(5H)-one(1417531-46-4)
• EPA Substance Registry System: 1-((5-((diethylamino)methyl)-4-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)isoxazol-3-yl)methyl)-2-(4-fluorobenzylthio)-6,7-dihydro-1H-cyclopenta[d]pyrimidin-4(5H)-one(1417531-46-4)

Safety Data

• Hazardous Substances Data: 1417531-46-4(Hazardous Substances Data)

Upstream product

• 1417531-66-8 C₂₀H₁₇F₃N₂O₃ 
• 1417531-44-2 2-(4-fluorobenzylthio)-1-((5-(hydroxymethyl)-4-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)isoxazol-3-yl)methyl)-6,7-dihydro-1H-cyclopenta[d]pyrimidin-4(5H)-one 
• 1417531-43-1 methyl 3-((2-(4-fluorobenzylthio)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-1-yl)methyl)-4-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)isoxazole-5-carboxylate 
• 1417531-64-6 methyl 3-((4-oxo-2-thioxo-2,3,4,5,6,7-hexahydro-1H-cyclopenta[d]pyrimidin-1-yl)methyl)-4-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)isoxazole-5-carboxylate 
• 1417531-65-7 methyl 3-((2-(ethoxycarbonyl)cyclopent-1-enylamino)methyl)-4-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)isoxazole-5-carboxylate 
• 1417531-67-9 methyl 3-((tert-butoxycarbonylamino)methyl)-4-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)isoxazole-5-carboxylate 
• 1417531-63-5 methyl 4-(4'-(trifluoromethyl)biphenyl-4-yl)buta-2,3-dienoate 
• 457889-46-2 (4′-(trifluoromethyl)-[1,1′-biphenyl]-4-yl)methanol 
• 613241-14-8 4-(bromomethyl)-4'-(trifluoromethyl)biphenyl 
• 90035-34-0 4-(4-trifluoromethylphenyl)benzaldehyde 
• 1417531-45-3 1-((5-(chloromethyl)-4-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)isoxazol-3-yl)methyl)-2-(4-fluorobenzylthio)-6,7-dihydro-1H-cyclopenta[d]pyrimidin-4(5H)-one 
• 109-89-7 diethylamine 
• 1122-91-4 4-bromo-benzaldehyde 
• 128796-39-4 4-trifluoromethylphenylboronic acid 

Relevant articles and documents

AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE

The present invention relates to the filed of pharmarcutical chemistry, and in particular, to a novel class of azole compounds represented by general formula (I), (II) or (III) amd a preparation method thereof, a pharmarcutical composition with the compounds as active components, and a use of the azole compounds and the pharmarcutical composition in the preparation of a medicament for treatment of diseases associated with Lp-PLA2 enzyme activities, wherein each substituent is as deinfed in the specifictaion.