457889-46-2

Basic information

• Product Name: (4'-TRIFLUOROMETHYLBIPHENYL-4-YL)-METHANOL
• Synonyms: (4-[4-(TRIFLUOROMETHYL)PHENYL]PHENYL)METHAN-1-OL;(4'-TRIFLUOROMETHYLBIPHENYL-4-YL)-METHANOL;[4'-(TRIFLUOROMETHYL)[1,1'-BIPHENYL]-4-YL]METHANOL;AKOS BAR-1788;RARECHEM AL BD 1218;4-(4-Trifluoromethyl)Benzyl Alcohol;4-(4-(Trifluoromethyl)phenyl)benzyl alcohol;4'-(TrifluoroMethyl)-[1,1'-biphenyl]-4-Methanol
• CAS NO: 457889-46-2
• Molecular Formula: C₁₄H₁₁F₃O
• Molecular Weight: 252.23
• Product Categories: pharmacetical
• Mol File: 457889-46-2.mol
• Article Data: 18

Chemical Properties

• Melting Point: 147-149°
• Boiling Point: 332.18 °C at 760 mmHg
• Flash Point: 136.784 °C
• Appearance: /
• Density: 1.248 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: (4'-TRIFLUOROMETHYLBIPHENYL-4-YL)-METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (4'-TRIFLUOROMETHYLBIPHENYL-4-YL)-METHANOL(457889-46-2)
• EPA Substance Registry System: (4'-TRIFLUOROMETHYLBIPHENYL-4-YL)-METHANOL(457889-46-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 457889-46-2(Hazardous Substances Data)

Usage

General Description

The chemical (4'-trifluoromethylbiphenyl-4-yl)-methanol is a compound that consists of a biphenyl ring with a trifluoromethyl group attached at the 4' position and a methanol group attached at the 4 position. It is a colorless liquid with a molecular formula of C14H11F3O. (4'-TRIFLUOROMETHYLBIPHENYL-4-YL)-METHANOL may be used in organic synthesis as a building block for the preparation of other chemical compounds. Additionally, it may have potential applications in the pharmaceutical or agrochemical industries due to its structural features. However, further research and testing are needed to fully understand its properties and potential uses.

Upstream product

• 402-43-7 p-trifluoromethylphenyl bromide 
• 59016-93-2 p-hydroxymethylphenylboronic acid 
• 90035-34-0 4-(4-trifluoromethylphenyl)benzaldehyde 
• 127783-73-7 methyl 4’-(trifluoromethyl)-[1,1’-biphenyl]-4-carboxylate 
• 195457-71-7 4-[4-(trifluoromethyl)phenyl]benzoic acid 
• 647842-34-0 ethyl 4'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxylate 
• 128796-39-4 4-trifluoromethylphenylboronic acid 
• 1122-91-4 4-bromo-benzaldehyde 
• 5798-75-4 Ethyl 4-bromobenzoate 
• 873-75-6 4-bromobenzenemethanol 

Downstream Products

• 454464-38-1 4-Chloromethyl-4'-trifluoromethyl-biphenyl 
• 613241-14-8 4-(bromomethyl)-4'-(trifluoromethyl)biphenyl 
• 1417526-64-7 1-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)-1H-benzo[d]imidazole 
• 1417531-67-9 methyl 3-((tert-butoxycarbonylamino)methyl)-4-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)isoxazole-5-carboxylate 
• 1417531-64-6 methyl 3-((4-oxo-2-thioxo-2,3,4,5,6,7-hexahydro-1H-cyclopenta[d]pyrimidin-1-yl)methyl)-4-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)isoxazole-5-carboxylate 
• 1417531-43-1 methyl 3-((2-(4-fluorobenzylthio)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-1-yl)methyl)-4-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)isoxazole-5-carboxylate 
• 1417531-44-2 2-(4-fluorobenzylthio)-1-((5-(hydroxymethyl)-4-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)isoxazol-3-yl)methyl)-6,7-dihydro-1H-cyclopenta[d]pyrimidin-4(5H)-one 
• 1417531-45-3 1-((5-(chloromethyl)-4-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)isoxazol-3-yl)methyl)-2-(4-fluorobenzylthio)-6,7-dihydro-1H-cyclopenta[d]pyrimidin-4(5H)-one 
• 1417531-46-4 1-((5-((diethylamino)methyl)-4-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)isoxazol-3-yl)methyl)-2-(4-fluorobenzylthio)-6,7-dihydro-1H-cyclopenta[d]pyrimidin-4(5H)-one 
• 1417531-66-8 C₂₀H₁₇F₃N₂O₃ 
• 1030367-96-4 2-(2-methyl-4-((2-phenyl-1-(4′-(trifluoromethyl)-[1,1′-biphenyl]-4-yl)ethyl)thio)phenoxy)acetic acid 
• 1030367-79-3 2-methyl-4-(((4′-(trifluoromethyl)-[1,1′-biphenyl]-4-yl)methyl)thio)phenol 
• 1030367-81-7 tert-butyl dimethyl(2-methyl-4-((2-phenyl-1-(4′-(trifluoromethyl)-[1,1′-biphenyl]-4-yl)ethyl)thio)phenoxy)silane 
• 1030367-80-6 tert-butyl dimethyl(2-methyl-4-(((4′-(trifluoromethyl)-[1,1′-biphenyl]-4-yl)methyl)thio)phenoxy)silane 

Relevant articles and documents

CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the enzyme ceramide galactosyltransferase (CGT), such as, for example, lysosomal storage diseases. Examples of lysosomal storage diseases include, for example, Krabbe disease and Metachromatic Leukodystrophy.

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AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE

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