1417658-13-9

Basic information

• Product Name: 5-chloro-N-(3-(trifluoromethyl)-2-trifluoromethylphenyl)-2-hydroxybenzamide
• CAS NO: 1417658-13-9
• Molecular Weight: 383.677
• Mol File: 1417658-13-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-chloro-N-(3-(trifluoromethyl)-2-trifluoromethylphenyl)-2-hydroxybenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-N-(3-(trifluoromethyl)-2-trifluoromethylphenyl)-2-hydroxybenzamide(1417658-13-9)
• EPA Substance Registry System: 5-chloro-N-(3-(trifluoromethyl)-2-trifluoromethylphenyl)-2-hydroxybenzamide(1417658-13-9)

Safety Data

• Hazardous Substances Data: 1417658-13-9(Hazardous Substances Data)

Upstream product

• 321-14-2 5-chloro-2-hydroxybenzoic acid 
• 1978-06-9 1,2-Bis(trifluoromethyl)-3-nitrobenzene 
• 433-95-4 1,2-bis(trifluoromethyl)benzene 

Relevant articles and documents

2-HYDROXYARYLAMIDE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER CONTAINING SAME AS ACTIVE INGREDIENT

The present invention relates to a 2-hydroxyarylamide derivative or a pharmaceutically acceptable salt thereof, a preparation method thereof, and a pharmaceutical composition for preventing or treating cancer comprising the same as an active ingredient. The 2-hydroxyarylamide derivative prepared by the present invention is excellent in the inhibition of the activity of TMPRSS4 serine protease and the suppression of the infiltration of TMPRSS4-expressed cancer cells, and thus can be useful as a composition for preventing or treating cancer by inhibiting TMPRSS4 over-expressed in cancer cells, particularly, colorectal cancer, lung cancer, breast cancer, prostate cancer, ovarian cancer, pancreatic cancer, or stomach cancer cells.