321-14-2 Usage
Description
5-Chloro-2-hydroxybenzoic acid, also known as 5-chlorosalicylic acid, is a monohydroxybenzoic acid derivative in which the hydrogen at position 5 is replaced by a chlorine atom. It is an off-white to cream-colored powder and is known for its various applications across different industries.
Uses
Used in Pharmaceutical Industry:
5-Chloro-2-hydroxybenzoic acid is used as an intermediate for the synthesis of various pharmaceutical compounds. Its unique chemical structure allows it to be a key component in the development of new drugs with potential therapeutic applications.
Used in Dye Industry:
In the dye industry, 5-Chloro-2-hydroxybenzoic acid is utilized as an intermediate for the production of various dyes. Its chemical properties make it suitable for creating a range of colors and hues in the dye manufacturing process.
Used in Pesticide Industry:
5-Chloro-2-hydroxybenzoic acid serves as an intermediate in the development of pesticides. Its chemical structure contributes to the effectiveness of these products in controlling and managing pests, thereby protecting crops and enhancing agricultural productivity.
Used in Insecticide Applications:
As an insecticide, 5-Chloro-2-hydroxybenzoic acid is employed to control and eliminate insects that can cause damage to crops or transmit diseases. Its chemical properties make it an effective agent in protecting plants and ensuring a healthy ecosystem.
Used in Moth-Proofing Applications:
In the textile industry, 5-Chloro-2-hydroxybenzoic acid is used for moth-proofing applications. Its chemical properties help protect fabrics and garments from damage caused by moths, extending their lifespan and maintaining their quality.
Hazard
Toxic by ingestion.
Check Digit Verification of cas no
The CAS Registry Mumber 321-14-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,2 and 1 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 321-14:
(5*3)+(4*2)+(3*1)+(2*1)+(1*4)=32
32 % 10 = 2
So 321-14-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H5ClO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,(H,10,11)/p-1
321-14-2Relevant articles and documents
Palladium-catalyzed ortho-C-H hydroxylation of benzoic acids
Luo, Feihua,He, Shuhua,Gou, Quan,Chen, Jinyang,Zhang, mingzhong
, (2021/10/06)
A simple Pd(OAc)2 catalyzed ortho-hydroxylation of benzoic acids using TBHP as the sole oxidant has been explored. This protocol features relatively broad substrate scope and operational simplicity. The compatibility of ortho-substituted substrates is an effective complement to the previous ortho-hydroxylation reaction.
In situ Generation of Hypervalent Iodine Reagents for the Electrophilic Chlorination of Arenes
Granados, Albert,Jia, Zhiyu,del Olmo, Marc,Vallribera, Adelina
, p. 2812 - 2818 (2019/04/08)
Efficient metal-free methods for the electrophilic chlorination of arenes using PIFA and simple chlorine sources are reported. The in situ formation of PhI(Cl)OCOCF3 from PIFA and KCl is proposed, which resulted in a chlorinating species for moderately activated arenes. Moreover, the in situ formation of PhICl2 from PIFA and TMSCl resulted in an excellent approach for the chlorination of a great variety of arenes (20 examples) in high yields, even when working on a multigram scale.
Rate enhancements due to ultrasound in isoquinolinium dichromate and isoquinolinium chlorochromate catalyzed chlorination of aromatic compounds in presence of KHSO4/KCl
Rajanna,Rao, A. Sambashiva,Chakravarthi,Reddy, K. Rajendar
, p. 167 - 170 (2017/12/26)
Chlorination of aromatic compounds underwent magnificent rate accelerations in isoquinolinium dichromate and isoquinolinium chlorochromate catalyzed chlorination of aromatic hydrocarbons in the presence of KCl and KHSO4. Reaction times reduced highly significantly from 4-5 h in conventional protocol to 30-40 min under sonication, followed by high yields of monochloro derivatives as products with high regioselectivity.