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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

5-Chlorosalicylic acid

Cas:321-14-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

Superiority pioneerbiotech is a leading manufacturer and supplier of chemicals in China. We develop ,produce and distribute high quality pharmaceuticals, intermediates, special chemicals and other fine chemicals. We could give you: 1.Best q

High Quality 5-Chlorosalicylic acid

Cas:321-14-2

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Other

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 5-chlorosalicylic acid

Cas:321-14-2

Min.Order:1

Negotiable

Type:Other

inquiry

EAST CHEMSOURCES LIMITED

An important fine chemical product is a raw material for the synthesis of some medicines and pesticides. Appearance:White crystal powder Storage:Stored in the ventilated, low temperature and dry room away from direct sunlight. Package:25kg/drum Appl

5-Chloro-2-hydroxybenzoic acid

Cas:321-14-2

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory price Cosmetic CHLOROSALICYLIC ACID 321-14-2 Manufacturer

Cas:321-14-2

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

CHemwill -- 5-Chlorosalicylic acid

Cas:321-14-2

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name: 5-Chloro-2-hydroxybenzoic acid Synonyms: 5-chloro-2-hydroxybenzoate;5-chloro-salicylicaci;Benzoic acid, 5-chloro-2-hydroxy-;Salicylic acid, 5-chloro-;CHLOROSALICYLIC(5-) ACID;5-CHLOROSALICYLIC ACID;5-CHLOROSALICYCLIC ACID;5-CHLORO-2-

5-Chloro-2-hydroxybenzoic acid 321-14-2

Cas:321-14-2

Min.Order:1 Kilogram

FOB Price: $230.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 321-14-2 with best price

Cas:321-14-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

5 CSA/JACS-321-14-2/5-Chlorosalicylic acid 321-14-2

Cas:321-14-2

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product Names: 5-Chloro-2-hydroxybenzoic acid CAS No.:321-14-2 MF: C7H5ClO3 NW: 172.57 Appearance: White powder Storage:Store in cool and dry place, away from sun light. Package:25KG/Drum Application:Agrochemical Intermediates, Dyestuff Inte

5-Chlorosalicylic acid

Cas:321-14-2

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

5-Chloro-2-hydroxybenzoic acid

Cas:321-14-2

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzoic acid,5-chloro-2-hydroxy- 321-14-2

Cas:321-14-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

5-Chloro-2-hydroxybenzoic acid CAS:321-14-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality orga

5-Chloro-2-hydroxybenzoic acid CAS:321-14-2

Cas:321-14-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzoic acid,5-chloro-2-hydroxy-

Cas:321-14-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:321-14-2

Cas:321-14-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

5-Chlorosalicylic acid

Cas:321-14-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

5-Chloro-2-hydroxybenzoic acid

Cas:321-14-2

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

5-Chlorosalicylic acid

Cas:321-14-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fonlynn Health Technology Co., Ltd.

Packing: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Transportation:Express/Sea/Air Port:Ningbo/Shanghai/Qingd

5-Chloro-2-hydroxybenzoic acid

Cas:321-14-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

5-Chloro-2-hydroxybenzoic acid/High quality/Best price

Cas:321-14-2

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High Quality 5-Chlorosalicylic acid

Cas:321-14-2

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

5-Chloro-2-hydroxybenzoic acid

Cas:321-14-2

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

5-Chloro-2-hydroxybenzoic acid

Cas:321-14-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

sell high purity of 5-Chloro-2-hydroxybenzoic acid

Cas:321-14-2

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hebei yanxi chemical co.,LTD.

CHENGDU YANXI is a comprehensive manufacturer and an international distribution of products throughout the world. Specialized in Scrap metal, Chemical raw materials, Paper products and color industry. We aim to become leading position in global dis

Pharmaceutical Intermediates 99% purity 5-Chlorosalicylic acid CAS No.:321-14-2

Cas:321-14-2

Min.Order:1 Kilogram

FOB Price: $1.0 / 3.0

Type:Trading Company

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

5-Chloro-2-hydroxybenzoic acid

Cas:321-14-2

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Hebei Mojin Biotechnology Co.,Ltd

1, High quality with competitive price:2, Fast and safe delivery3.Excellent pre-sales and after-sales service4. Well-trained and professional technologist and sales with rich experience in the field for 5-10 yearsAppearance:see detailed specification

Benzoic acid,5-chloro-2-hydroxy-

Cas:321-14-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

5-Chlorosalicyclic acid

Cas:321-14-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

5-Chloro-2-hydroxybenzoic acid

Cas:321-14-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Best service,high quality and cheap price. Storage:Keep away from heat,sparks and flames. Package:25kg/50kg/200kg drum or Customer demand Application:Used as pharmaceutical intermediates Transportation:BY sea/air or by courier

5-Chlorosalicylic acid

Cas:321-14-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

carbon dioxide
124-38-9

carbon dioxide

4-chloro-phenol
106-48-9

4-chloro-phenol

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Stage #1: 4-chloro-phenol With sodium hydroxide In water for 2h; Autoclave; Reflux;
Stage #2: carbon dioxide In N,N-dimethyl-formamide at 80 - 145℃; under 2250.23 - 3750.38 Torr; for 15h; Autoclave;
Stage #3: With sulfuric acid In 5,5-dimethyl-1,3-cyclohexadiene pH=6.5;
97.65%
Stage #1: 4-chloro-phenol With Mesitol; sodium hydride In mineral oil at 100℃; for 0.0833333h; Glovebox;
Stage #2: carbon dioxide In mineral oil at 185℃; under 760.051 Torr; for 2h;
85%
With potassium carbonate at 140℃; under 29420.3 Torr;
3-chlorobenzoate
535-80-8

3-chlorobenzoate

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With oxygen; potassium acetate; palladium diacetate; p-benzoquinone In N,N-dimethyl acetamide at 115℃; under 3800.26 Torr; for 15h;95%
With oxygen; potassium acetate; p-benzoquinone; palladium diacetate In ISOPROPYLAMIDE at 115℃; under 3800.26 Torr; for 15h; Product distribution / selectivity;95%
Multi-step reaction with 2 steps
1: fuming nitric acid / Reduzieren des Nitrierungsprodukts mit Zinn und Salzsaeure
2: water; nitrous acid
View Scheme
salicylic acid
69-72-7

salicylic acid

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Stage #1: salicylic acid With sulfuric acid In acetonitrile at 20℃; for 0.0833333h;
Stage #2: With N-chloro-succinimide In acetonitrile at 20℃; for 2.5h; regioselective reaction;
92%
With sodium periodate; sulfuric acid; sodium dodecyl-sulfate; acetic acid; sodium chloride In water at 25℃; for 2h;85%
With hydrogenchloride; sodium percarbonate; dihydrogen peroxide In dichloromethane; water at 40 - 45℃; Reagent/catalyst; Solvent; Green chemistry;82.5%
2,5-dichlorobenzoic acid
50-79-3

2,5-dichlorobenzoic acid

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With pyridine; water; potassium carbonate; copper for 0.25h; sonication;92%
With pyridine; copper; potassium carbonate In water for 2h; Heating;84%
With sodium methylate at 150℃; Eintragen des Reaktionsgemisches in Wasser;
With copper(l) iodide; copper; potassium carbonate at 170℃; under 4413.05 Torr;
sodium ethyl carbonate
17201-44-4

sodium ethyl carbonate

4-chloro-phenol
106-48-9

4-chloro-phenol

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With carbon dioxide at 190℃; under 7600.51 Torr; for 6h; Time; Temperature; Pressure; Autoclave; regioselective reaction;86.1%
2-bromo-5-chlorobenzoic acid
21739-93-5

2-bromo-5-chlorobenzoic acid

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With copper(I) oxide; 2-pyridinealdoxime; cesium hydroxide; tetrabutylammomium bromide In water at 100℃; for 48h; Inert atmosphere;81%
6-chloro-2-methyl-4H-chromen-4-one
69693-00-1

6-chloro-2-methyl-4H-chromen-4-one

furan-2,3,5(4H)-trione pyridine (1:1)

furan-2,3,5(4H)-trione pyridine (1:1)

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

2-methyl-4-chloroanisole
3260-85-3

2-methyl-4-chloroanisole

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With potassium permanganate beim Erwaermen mit Jodwasserstoffsaeure;
5-chloro-2-hydroxybenzonitrile
13589-72-5

5-chloro-2-hydroxybenzonitrile

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With sulfuric acid; water at 200℃;
5,5'-thio-bis(2-hydroxy-benzoic acid)
1820-99-1

5,5'-thio-bis(2-hydroxy-benzoic acid)

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With sulfuryl dichloride; benzene
tetrachloromethane
56-23-5

tetrachloromethane

4-chloro-phenol
106-48-9

4-chloro-phenol

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With sodium hydroxide
4-chloro-phenol
106-48-9

4-chloro-phenol

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With tetrachloromethane; potassium hydroxide; ethanol at 140℃; im geschlossenen Rohr;
Multi-step reaction with 4 steps
1.1: 1H-imidazole / N,N-dimethyl-formamide / 0.5 h / 0 - 20 °C / Inert atmosphere
1.2: 0 - 20 °C / Inert atmosphere
2.1: water; sodium hydrogencarbonate / N,N-dimethyl-formamide; diethyl ether / 0.5 h / 20 °C / Inert atmosphere
3.1: palladium diacetate; silver(I) acetate; N-tert-butoxycarbonyl-L-leucine; 2,2,2-trifluoroethanol / 1,2-dichloro-ethane / 0.08 h / 95 °C / Inert atmosphere
3.2: 18 h / 95 °C / Inert atmosphere
4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / Inert atmosphere
View Scheme
With oxygen; potassium acetate; palladium diacetate; p-benzoquinone In N,N-dimethyl acetamide at 115℃; for 15h; Schlenk technique; regioselective reaction;
With tetrachloromethane; sodium hydroxide; copper
5-chloroanthranilic acid
635-21-2

5-chloroanthranilic acid

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With water; cis-nitrous acid
N,N-dichloro-p-toluenesulfonamide
473-34-7

N,N-dichloro-p-toluenesulfonamide

salicylic acid
69-72-7

salicylic acid

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With chloroform
salicylic acid
69-72-7

salicylic acid

A

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

B

3,5-dichlorosalicylic acid
320-72-9

3,5-dichlorosalicylic acid

Conditions
ConditionsYield
With ethanol; chlorine
With tert-butylhypochlorite In water
With ethanol beim Chlorieren; Trennung ueber die Bariumsalze;
With antimonypentachloride
salicylic acid
69-72-7

salicylic acid

A

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

B

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With sodium carbonate bei der Chlorierung;
With sodium hydroxide; sodium hypochlorite at 20℃; for 2.5h; pH > 12; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With N-chlorotriethylammonium chloride In trifluoroacetic acid Ambient temperature; Yield given. Yields of byproduct given;
2-hydroxy-benzoic acid ethyl ester
118-61-6

2-hydroxy-benzoic acid ethyl ester

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With sulfuryl dichloride Behandeln mit Kalilauge;
2-acetoxy-5-chloro-benzoic acid
1734-62-9

2-acetoxy-5-chloro-benzoic acid

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With sodium hydroxide; alpha cyclodextrin In water at 25℃; Rate constant; Ionic strength: 1.0 (NaCl); effect of pH, concentration of α-cyclodextrin;
With water at 25℃; Kinetics;
4-chlorosalicylate
45866-17-9

4-chlorosalicylate

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
In ethanol; water at 25℃; Equilibrium constant;
6-chloro-2-methyl-4H-chromen-4-one
69693-00-1

6-chloro-2-methyl-4H-chromen-4-one

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With sodium hydroxide; dihydrogen peroxide In methanol at 20℃; Oxidation;
Multi-step reaction with 2 steps
1: 59 percent / AcONa / 2 h / 260 - 270 °C
2: 10 percent aq. NaOH / ethanol / 4 h / Heating
View Scheme
Multi-step reaction with 2 steps
1: 88 percent / Na / diethyl ether
2: 10 percent aq. KOH
View Scheme
3-(6-chloro-4-oxo-4H-chromen-2-yl)-2-oxo-propionic acid ethyl ester
144880-76-2

3-(6-chloro-4-oxo-4H-chromen-2-yl)-2-oxo-propionic acid ethyl ester

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With potassium hydroxide Hydrolysis;
6-Chloro-2-(3-phthalidenemethylene)chromone
144880-82-0

6-Chloro-2-(3-phthalidenemethylene)chromone

A

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

B

benzene-1,2-dicarboxylic acid
88-99-3

benzene-1,2-dicarboxylic acid

Conditions
ConditionsYield
With sodium hydroxide In ethanol for 4h; Hydrolysis; Heating;
6-chloro-2,3-dimethyl-chromen-4-one
99852-42-3

6-chloro-2,3-dimethyl-chromen-4-one

diluted alkali

diluted alkali

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

6-Chloro-chromen-2-one
2051-59-4

6-Chloro-chromen-2-one

potassium hydroxide

potassium hydroxide

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
beim Schmelzen;
6-chloro-2,3-diphenyl-4H-chromen-4-one

6-chloro-2,3-diphenyl-4H-chromen-4-one

KOH-solution

KOH-solution

A

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

B

benzoic acid
65-85-0

benzoic acid

C

4-chloro-2-phenacetyl-phenol

4-chloro-2-phenacetyl-phenol

water
7732-18-5

water

cis-nitrous acid
7782-77-6

cis-nitrous acid

5-chloroanthranilic acid
635-21-2

5-chloroanthranilic acid

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

chlorine
7782-50-5

chlorine

nitrobenzene
98-95-3

nitrobenzene

salicylic acid
69-72-7

salicylic acid

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

5-chlorosalicyclaldehyde
635-93-8

5-chlorosalicyclaldehyde

chromic acid

chromic acid

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

tetrachloromethane
56-23-5

tetrachloromethane

4-chloro-phenol
106-48-9

4-chloro-phenol

furan-2,3,5(4H)-trione pyridine (1:1)

furan-2,3,5(4H)-trione pyridine (1:1)

copper

copper

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
bei Siedetemperatur;
tetrachloromethane
56-23-5

tetrachloromethane

ethanol
64-17-5

ethanol

4-chloro-phenol
106-48-9

4-chloro-phenol

KOH

KOH

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
at 140℃;
5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

3-Chloro-2-methylpropene
563-47-3

3-Chloro-2-methylpropene

2-methylallyl 5-chloro-2-(2-methylallyloxy)benzoate

2-methylallyl 5-chloro-2-(2-methylallyloxy)benzoate

Conditions
ConditionsYield
Stage #1: 5-chloro-2-hydroxybenzoic acid With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 65℃; for 0.0833333h; Inert atmosphere;
Stage #2: 3-Chloro-2-methylpropene In N,N-dimethyl-formamide at 65℃; for 21h;
100%
With potassium carbonate In N-methyl-acetamide
5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

2-Methylphenylboronic acid
16419-60-6

2-Methylphenylboronic acid

4-hydroxy-2'-methylbiphenyl-3-carboxylic acid
25205-15-6

4-hydroxy-2'-methylbiphenyl-3-carboxylic acid

Conditions
ConditionsYield
With sodium 2'‐(dicyclohexylphosphaneyl)‐2,6‐diisopropyl‐[1,1'‐biphenyl]‐3‐sulfonate; palladium diacetate; potassium carbonate In water at 20℃; for 12h; Suzuki-Miyaura coupling;99%
5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

4-chloro-2-hydroxymethylphenol
5330-38-1

4-chloro-2-hydroxymethylphenol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In diethyl ether for 0.75h; Heating;97%
With sodium tetrahydroborate; Trimethyl borate; dimethyl sulfate In tetrahydrofuran at 20℃; for 4.5h;96%
With borane-THF; boron trifluoride diethyl etherate In tetrahydrofuran at 20℃; for 18h;85%
5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

acetic anhydride
108-24-7

acetic anhydride

2-acetoxy-5-chloro-benzoic acid
1734-62-9

2-acetoxy-5-chloro-benzoic acid

Conditions
ConditionsYield
With sulfuric acid for 3h; Heating / reflux;97%
With sulfuric acid93%
With sulfuric acid93%
5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

tributyltin chloride
1461-22-9

tributyltin chloride

C19H31ClO3Sn

C19H31ClO3Sn

Conditions
ConditionsYield
Stage #1: 5-chloro-2-hydroxybenzoic acid With potassium hydroxide In methanol at 20℃; for 1h;
Stage #2: tributyltin chloride In methanol for 5h;
97%
zirconocene dichloride
1291-32-3

zirconocene dichloride

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

[Cp2Zr(μ2-O',O''C-C6H3(OH)Cl)2]
1192558-54-5

[Cp2Zr(μ2-O',O''C-C6H3(OH)Cl)2]

Conditions
ConditionsYield
In hydrogenchloride; dichloromethane mixt. of zirconocene dichloride in 1 M aq. HCl and dichlorobenzoic acidin CH2Cl2 was stirred for 30 min at room temp.; organic layer was separated, dried over MgSO4, filtered, concd. in vac.,crystd. form CH2Cl2/Et2O/hexane, elem. anal.;96.3%
5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

5-chloro-2-hydroxy-3-nitrobenzoic acid
7195-78-0

5-chloro-2-hydroxy-3-nitrobenzoic acid

Conditions
ConditionsYield
With sulfuric acid; nitric acid at 20℃;96%
With sulfuric acid; nitric acid at 0 - 20℃; for 5.66667h;95%
With sulfuric acid; nitric acid for 6h; Ambient temperature;90.5%
5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

3-bromo-5-chloro-2-hydroxy benzoic acid
4068-58-0

3-bromo-5-chloro-2-hydroxy benzoic acid

Conditions
ConditionsYield
With bromine In chloroform96%
With N-Bromosuccinimide In carbon disulfide at 25℃; for 14h;
With bromine; acetic acid at 80℃; for 8h;204.6 g
With bromine; acetic acid at 80℃; for 8h;204.6 g
dichloromethane
75-09-2

dichloromethane

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

6-chloro-4H-benzo[d][1,3]dioxin-4-one
342411-03-4

6-chloro-4H-benzo[d][1,3]dioxin-4-one

Conditions
ConditionsYield
With potassium phosphate tribasic trihydrate In N,N-dimethyl-formamide at 100℃; under 760.051 Torr; for 6h; Green chemistry;96%
5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

5,5-dibenzyl-2,3,4,5-tetrahydropyridine
1416767-53-7

5,5-dibenzyl-2,3,4,5-tetrahydropyridine

6,6-dibenzyl-2-chloro-6,7,8,9-tetrahydro-5aH,11H-pyrido[2,1-b][1,3]benzoxazin-11-one

6,6-dibenzyl-2-chloro-6,7,8,9-tetrahydro-5aH,11H-pyrido[2,1-b][1,3]benzoxazin-11-one

Conditions
ConditionsYield
With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; N-ethyl-N,N-diisopropylamine In toluene at 90℃; for 20h;96%
5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

acetyl chloride
75-36-5

acetyl chloride

2-acetoxy-5-chloro-benzoic acid
1734-62-9

2-acetoxy-5-chloro-benzoic acid

Conditions
ConditionsYield
With pyridine; sulfuric acid In toluene95.6%
With triethylamine In tetrahydrofuran at 20℃;46.7%
sebacoyl chloride
111-19-3

sebacoyl chloride

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

1,10-bis-4-chlorosalicyl-sebacate

1,10-bis-4-chlorosalicyl-sebacate

Conditions
ConditionsYield
Stage #1: sebacoyl chloride; 5-chloro-2-hydroxybenzoic acid With pyridine In tetrahydrofuran for 2h;
Stage #2: With hydrogenchloride In tetrahydrofuran; water pH=2;
95%
5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

dibutyltin chloride
683-18-1

dibutyltin chloride

2C7H4ClO3(1-)*Sn(4+)*2C4H9(1-)

2C7H4ClO3(1-)*Sn(4+)*2C4H9(1-)

Conditions
ConditionsYield
Stage #1: 5-chloro-2-hydroxybenzoic acid With potassium hydroxide In methanol at 20℃; for 1h;
Stage #2: dibutyltin chloride In methanol for 5h;
95%
5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

2,4-difluorophenylboronic acid
144025-03-6

2,4-difluorophenylboronic acid

2',4'-difluoro-4-hydroxybiphenyl-3-carboxylic acid
22494-42-4

2',4'-difluoro-4-hydroxybiphenyl-3-carboxylic acid

Conditions
ConditionsYield
With bis(di-tert-butyl(4-dimethylaminophenyl)phosphine)dichloropalladium(II); tetrabutylammomium bromide; potassium carbonate In ethanol; water for 8h; Concentration; Reagent/catalyst; Suzuki Coupling; Inert atmosphere; Reflux;95%
5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

2-[(N,N-dimethylamino)methyl]ferrocenylmethylamine

2-[(N,N-dimethylamino)methyl]ferrocenylmethylamine

C21H23ClFeN2O2

C21H23ClFeN2O2

Conditions
ConditionsYield
With pyridine; dicyclohexyl-carbodiimide at 80℃; for 2h; Microwave irradiation;95%
5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

methyl 5-chloro-2-hydroxybenzoate
4068-78-4

methyl 5-chloro-2-hydroxybenzoate

Conditions
ConditionsYield
With sulfuric acid In methanol94.8%
With thionyl chloride In methanol; ethyl acetate74%
With thionyl chloride In methanol; ethyl acetate74%
conc. H2 SO4

conc. H2 SO4

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

methyl 5-chloro-2-hydroxybenzoate
4068-78-4

methyl 5-chloro-2-hydroxybenzoate

Conditions
ConditionsYield
In methanol94.8%
methanol
67-56-1

methanol

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

methyl 5-chloro-2-hydroxybenzoate
4068-78-4

methyl 5-chloro-2-hydroxybenzoate

Conditions
ConditionsYield
With thionyl chloride for 168h; Inert atmosphere; Reflux;94%
With sulfuric acid for 120h; Inert atmosphere; Reflux;91%
With sulfuric acid for 120h; Reflux;91%
5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

triphenyltin chloride
639-58-7

triphenyltin chloride

C25H19ClO3Sn

C25H19ClO3Sn

Conditions
ConditionsYield
Stage #1: 5-chloro-2-hydroxybenzoic acid With potassium hydroxide In methanol at 20℃; for 1h;
Stage #2: triphenyltin chloride In methanol for 5h;
94%
2-fluoroethyl bromide
762-49-2

2-fluoroethyl bromide

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

2-fluoroethyl 5-chloro-2-(2-fluoroethoxy)benzoate
334652-76-5

2-fluoroethyl 5-chloro-2-(2-fluoroethoxy)benzoate

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 80℃; for 48h;93.4%
With sodium hydride
bis(3-bromopropyl) ether
58929-72-9

bis(3-bromopropyl) ether

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

5-chloro-2-(2-methoxyethoxy)benzoic acid 2-methoxyethyl ester
521065-04-3

5-chloro-2-(2-methoxyethoxy)benzoic acid 2-methoxyethyl ester

Conditions
ConditionsYield
With potassium carbonate In ethyl acetate; acetonitrile93%
5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

copper dichloride

copper dichloride

5-chloro-2-hydroxy benzoic acid copper (II) salt

5-chloro-2-hydroxy benzoic acid copper (II) salt

Conditions
ConditionsYield
Stage #1: 5-chloro-2-hydroxybenzoic acid With sodium hydroxide In water
Stage #2: copper dichloride In water for 24h;
93%
5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

4-cyanophenylboronic acid
126747-14-6

4-cyanophenylboronic acid

4'-cyano-4-hydroxybiphenyl-3-carboxylic acid

4'-cyano-4-hydroxybiphenyl-3-carboxylic acid

Conditions
ConditionsYield
With sodium 2'‐(dicyclohexylphosphaneyl)‐2,6‐diisopropyl‐[1,1'‐biphenyl]‐3‐sulfonate; palladium diacetate; potassium carbonate In water at 80℃; for 12h; Suzuki-Miyaura coupling;92%
5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

dibutyltin chloride
683-18-1

dibutyltin chloride

C15H22Cl2O3Sn

C15H22Cl2O3Sn

Conditions
ConditionsYield
Stage #1: 5-chloro-2-hydroxybenzoic acid With potassium hydroxide In methanol at 20℃; for 1h;
Stage #2: dibutyltin chloride In methanol for 5h;
92%
bis(cyclopentadienyl)titanium dichloride
1271-19-8

bis(cyclopentadienyl)titanium dichloride

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

Ti(η5-C5H5)2(C6H3Cl(O)(CO2))
233600-03-8

Ti(η5-C5H5)2(C6H3Cl(O)(CO2))

Conditions
ConditionsYield
With NaOH; catalyst: C2H5OH In ethanol; chloroform; water-d2 Kinetics; NaOH and C2H5OH added to mixt. of (C5H5)2TiCl2 and acid dissolved in CHCl3, stirred for 30 min at room temp.; dried (anhydrous MgSO4), filtered, filtrate concd. in vac., ppt. recrystd. from CH2Cl2/hexane; elem. anal.;91.1%
5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

trimethyltin(IV)chloride
1066-45-1

trimethyltin(IV)chloride

C10H13ClO3Sn

C10H13ClO3Sn

Conditions
ConditionsYield
Stage #1: 5-chloro-2-hydroxybenzoic acid With potassium hydroxide In methanol at 20℃; for 1h;
Stage #2: trimethyltin(IV)chloride In methanol for 5h;
91%

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