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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

3-Chlorosalicylic acid Manufacturer/High quality/Best price/In stock

Cas:1829-32-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Changzhou Anchor Biological Technology Co., Ltd.

Our company is engaged in customizing the benzene ring and pyridine derivative organic intermediates, and the quantity is flexible according to customer's needs. It mainly provides high-quality intermediates for domestic and foreign pharmaceuti

3-Chloro-2-hydroxybenzoic acid CAS:1829-32-9

Cas:1829-32-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3-Chlorosalicylic acid

Cas:1829-32-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung, LG, Merck, Thermo Fisher Scientific and so o

1829-32-9 3-Chlorosalicylic acid

Cas:1829-32-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 1829-32-9 with best quality

Cas:1829-32-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

3-Chlorosalicylic acid 1829-32-9

Cas:1829-32-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

3-Chlorosalicylic acid CAS:1829-32-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic int

3-Chlorosalicylic acid CAS:1829-32-9

Cas:1829-32-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

3-Chlorosalicylic acid

Cas:1829-32-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

3-Chlorosalicylic acid CAS:1829-32-9

Cas:1829-32-9

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

3-Chlorosalicylic acid

Cas:1829-32-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3-Chlorosalicylic acid

Cas:1829-32-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

3-Chloro-2-hydroxybenzoic acid

Cas:1829-32-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 3-Chlorosalicylic acid Synonyms: 3-CHLORO-2-HYDROXYBENZOIC ACID;3-CHLOROSALICYLIC ACID;Salicylic acid, 3-chloro-;Benzoic acid, 3-chloro-2-hydroxy-;2-Hydroxy-3-chlorobenzoic acid;3-Chlorosalicylic acid,98%;3-Chlorosalicylic acid 98

3-Chlorosalicylic acid

Cas:1829-32-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

3-Chlorosalicylic acid

Cas:1829-32-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

3-Chlorosalicylic Acid cas no. 1829-32-9 98%

Cas:1829-32-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

3-Chlorosalicylic acid

Cas:1829-32-9

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

3-Chloro-2-hydroxybenzoic acid

Cas:1829-32-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

3-Chlorosalicylic acid

Cas:1829-32-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

3-Chlorosalicylic acid

Cas:1829-32-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Nanjing Fred Technology Co.,Ltd.

Fredchem focus on CRO/CMO business and its own R&D of API/Intermediates Package:Grams, Kilograms Application:Pharmaceutical field Transportation:According to customer request Port:Shanghai

3-Chlorosalicylic acid

Cas:1829-32-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

3-Chlorosalicylic acid

Cas:1829-32-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Pharm intermediate

3-Chlorosalicylic acid

Cas:1829-32-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

3-Chlorosalicylic acid cas 1829-32-9Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

3-Chlorosalicylic acid cas 1829-32-9

Cas:1829-32-9

Min.Order:0

Negotiable

Type:Other

inquiry

Changzhou Ansciep Chemical Co.,Ltd.

reagent grade ex stockAppearance:white or off-white crystalline powder Storage:Keep away of light,cool place Package:1L 5L 10L 25L bottle Application:pharma intermediate Transportation:by Fedex, ship or plane

3-CHLORO-2-HYDROXYBENZOIC ACID;

Cas:1829-32-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Best quality with low price Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

3-Chlorosalicylic acid

Cas:1829-32-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

3-Chlorosalicylic acid

Cas:1829-32-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

3-chloro-2-hydroxybenzoic acid

Cas:1829-32-9

Min.Order:0

Negotiable

Type:Other

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

1829-32-9

Cas:1829-32-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

3-Chlorosalicylic acid 1829-32-9

Cas:1829-32-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

3-Chlorosalicylic acid

Cas:1829-32-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

3-chloro-2-hydroxy-thiobenzoic acid S-methyl ester
116025-20-8

3-chloro-2-hydroxy-thiobenzoic acid S-methyl ester

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With lithium hydroxide In methanol at 20℃; for 6h;100%
carbon dioxide
124-38-9

carbon dioxide

chloro-1 methoxymethylenoxy-2 benzene
27701-22-0

chloro-1 methoxymethylenoxy-2 benzene

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Stage #1: chloro-1 methoxymethylenoxy-2 benzene With n-butyllithium In tetrahydrofuran; hexane at 0℃; for 1.5h;
Stage #2: carbon dioxide In tetrahydrofuran; hexane at -78℃; for 1.5h;
Stage #3: With hydrogenchloride In tetrahydrofuran; hexane at 20℃;
91%
2,3-dichlorbenzoic acid
50-45-3

2,3-dichlorbenzoic acid

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With pyridine; copper; potassium carbonate In water for 2h; Heating;85%
With copper(l) iodide; copper; potassium carbonate at 180℃; under 7355.08 Torr;
N-(4-fluorophenyl)glycine potassium salt

N-(4-fluorophenyl)glycine potassium salt

A

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

B

N-(4-fluorophenyl)-N-(2-carboxyphenyl)glycin
180911-99-3

N-(4-fluorophenyl)-N-(2-carboxyphenyl)glycin

Conditions
ConditionsYield
Stage #1: N-(4-fluorophenyl)glycine potassium salt With potassium 2,5-dichlorobenzoate; copper; potassium carbonate In water for 20.5h; Heating / reflux;
Stage #2: With hydrogenchloride In water at 75 - 80℃; for 0.5h;
A n/a
B 80.3%
2-monochlorophenol
95-57-8

2-monochlorophenol

sodium ethyl carbonate
17201-44-4

sodium ethyl carbonate

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With carbon dioxide at 190℃; under 7600.51 Torr; for 6h; Autoclave; regioselective reaction;68.2%
carbon dioxide
124-38-9

carbon dioxide

2-monochlorophenol
95-57-8

2-monochlorophenol

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Stage #1: 2-monochlorophenol With Mesitol; sodium hydride In mineral oil at 100℃; for 0.0833333h; Glovebox;
Stage #2: carbon dioxide In mineral oil at 185℃; under 3800.26 Torr; for 2h;
55%
With potassium carbonate at 170℃; under 29420.3 Torr;
3-chloro-2-hydroxy-benzoic acid-(2,2,2-trichloro-1-hydroxy-ethylamide)
873975-79-2

3-chloro-2-hydroxy-benzoic acid-(2,2,2-trichloro-1-hydroxy-ethylamide)

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With sodium hydroxide
salicylic acid disodium salt
54-21-7, 13639-21-9, 79211-80-6

salicylic acid disodium salt

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With sodium hypochlorite
5-sulfosalicylic Acid
97-05-2

5-sulfosalicylic Acid

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With chlorine; acetic acid Behandeln des Reaktionsprodukts mit ueberhitztem Wasserdampf;
With hydrogenchloride; potassium permanganate Behandeln des Reaktionsprodukts mit ueberhitztem Wasserdampf;
tetrachloromethane
56-23-5

tetrachloromethane

tert-butylhypochlorite
507-40-4

tert-butylhypochlorite

salicylic acid
69-72-7

salicylic acid

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

tert-butylhypochlorite
507-40-4

tert-butylhypochlorite

salicylic acid
69-72-7

salicylic acid

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With tetrachloromethane
salicylic acid
69-72-7

salicylic acid

A

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

B

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With sodium carbonate bei der Chlorierung;
With sodium hydroxide; sodium hypochlorite at 20℃; for 2.5h; pH > 12; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With N-chlorotriethylammonium chloride In trifluoroacetic acid Ambient temperature; Yield given. Yields of byproduct given;
3-chlorosalicylaldehyde
1927-94-2

3-chlorosalicylaldehyde

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With sodium hydroxide; potassium permanganate Heating;
2-amino-3-chlorobenzoic acid
6388-47-2

2-amino-3-chlorobenzoic acid

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With copper(II) sulfate 1.) diazotized; Yield given. Multistep reaction;
dipotassium 5-chlorosalicyl sulphate

dipotassium 5-chlorosalicyl sulphate

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With HCl-chloroacetate; potassium chloride at 70℃; Rate constant; dependence on pH;
7-chloro-1,1-dioxo-1,2-dihydro-1λ6-benzo[d]isothiazol-3-one
89999-91-7

7-chloro-1,1-dioxo-1,2-dihydro-1λ6-benzo[d]isothiazol-3-one

water
7732-18-5

water

sodium hydroxide

sodium hydroxide

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
beim Schmelzen;
chlorine
7782-50-5

chlorine

acetic acid
64-19-7

acetic acid

5-sulfosalicylic Acid
97-05-2

5-sulfosalicylic Acid

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Behandeln des Reaktionsprodukts mit Wasserdampf;
carbon dioxide
124-38-9

carbon dioxide

2-chloro-phenol sodium

2-chloro-phenol sodium

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
at 140 - 150℃; im Autoklaven;
2-hydroxy-1-carboxy-benzenediazonium-(3)-betaine

2-hydroxy-1-carboxy-benzenediazonium-(3)-betaine

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With hydrogenchloride Sonnenlicht;
sodium salicylate
54-21-7

sodium salicylate

chlorine
7782-50-5

chlorine

natrium carbonate

natrium carbonate

A

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

B

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

3-chloro-2-methoxymethoxy-benzoic acid

3-chloro-2-methoxymethoxy-benzoic acid

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With hydrogenchloride In water pH=1;3.19 g
3-chlorobenzoate
535-80-8

3-chlorobenzoate

A

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

B

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Stage #1: 3-chlorobenzoate With [bis(acetonitrile)(N,N'-dimethyl-N,N'-bis(2-pyridylmethyl)-1,2-diaminoethane)iron(II)] perchlorate; dihydrogen peroxide In acetonitrile at 20℃; for 0.333333h;
Stage #2: With hydrogenchloride In acetonitrile
With [Fe(II)(N,N'-dimethyl-N,N'-bis(2-pyridylmethyl)-1,2-ethylenediamine)(CH3CN)2](ClO4)2; dihydrogen peroxide In water; acetonitrile at 20℃; Inert atmosphere; regioselective reaction;
chloro-1 methoxymethylenoxy-2 benzene
27701-22-0

chloro-1 methoxymethylenoxy-2 benzene

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: butyllithium / tetrahydrofuran; hexane / 6 h / -75 °C
1.2: tetrahydrofuran; hexane
2.1: 3.19 g / HCl / H2O / pH 1
View Scheme
2-monochlorophenol
95-57-8

2-monochlorophenol

(+-)-ethylphosphonic acid ethyl ester chloride

(+-)-ethylphosphonic acid ethyl ester chloride

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: BCl3; AlCl3 / 1,2-dichloro-ethane / 4 h / 20 °C
1.2: 51 percent / aq. HCl / 1,2-dichloro-ethane / 0.17 h / 20 °C
2.1: 100 percent / aq. LiOH / methanol / 6 h / 20 °C
View Scheme
2-monochlorophenol
95-57-8

2-monochlorophenol

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 96 percent / NaH / tetrahydrofuran; methyl acetate / 2 h / 0 - 20 °C
2.1: n-BuLi / tetrahydrofuran; hexane / 1.5 h / 0 °C
2.2: tetrahydrofuran; hexane / 1.5 h / -78 °C
2.3: 91 percent / 6M HCl / tetrahydrofuran; hexane / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: (i) aq. NaOH, (ii) /BRN= 1731042/
2: KMnO4, aq. NaOH / Heating
View Scheme
Multi-step reaction with 4 steps
1.1: 1H-imidazole / N,N-dimethyl-formamide / 0.5 h / 0 - 20 °C / Inert atmosphere
1.2: 0 - 20 °C / Inert atmosphere
2.1: water; sodium hydrogencarbonate / N,N-dimethyl-formamide; diethyl ether / 0.5 h / 20 °C / Inert atmosphere
3.1: palladium diacetate; silver(I) acetate; N-tert-butoxycarbonyl-L-leucine; 2,2,2-trifluoroethanol / 1,2-dichloro-ethane / 0.08 h / 95 °C / Inert atmosphere
3.2: 18 h / 95 °C / Inert atmosphere
3.3: 18 h / 95 °C / Inert atmosphere; Glovebox
4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / Inert atmosphere
View Scheme
3-chloro-2-nitro-benzoic acid
4771-47-5

3-chloro-2-nitro-benzoic acid

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 72 percent / tin, hydrochloric acid
2: 2.) CuSO4 / 1.) diazotized
View Scheme
potassium 2,5-dichlorobenzoate

potassium 2,5-dichlorobenzoate

N-(4-fluorophenyl)glycine potassium salt

N-(4-fluorophenyl)glycine potassium salt

A

N-(4-fluorophenyl)-N-(2-carboxy-4-chlorophenyl)glycine

N-(4-fluorophenyl)-N-(2-carboxy-4-chlorophenyl)glycine

B

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With potassium carbonate; copper In water at 50℃; for 15 - 20.5h; Heating / reflux; Industry scale;
2-monochlorophenol
95-57-8

2-monochlorophenol

potassium hydrogencarbonate
298-14-6

potassium hydrogencarbonate

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With 2,3-dihydroxybenzoate decarboxylase from Aspergillus oryzae In aq. phosphate buffer at 30℃; for 24h; Kolbe-Schmidt Synthesis; Enzymatic reaction; regioselective reaction;
salicylic acid
69-72-7

salicylic acid

A

5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

B

3,5-dichlorosalicylic acid
320-72-9

3,5-dichlorosalicylic acid

C

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

Conditions
ConditionsYield
With sodium hypochlorite In methanol; water
3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

methyl iodide
74-88-4

methyl iodide

methyl 3-chloro-2-methoxybenzoate

methyl 3-chloro-2-methoxybenzoate

Conditions
ConditionsYield
With potassium carbonate In DMF (N,N-dimethyl-formamide) at 80℃; for 23h;100%
With potassium carbonate In N-methyl-acetamide
formaldehyd
50-00-0

formaldehyd

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

3,3'-dicarboxy-5,5'-dichloro-4,4'-dihydroxydiphenylmethane
128626-47-1

3,3'-dicarboxy-5,5'-dichloro-4,4'-dihydroxydiphenylmethane

Conditions
ConditionsYield
With sulfuric acid In methanol; water 1.)0 deg C, 1h 2.) r. t., 24h;96%
With sulfuric acid In methanol; water at -5 - 0℃; for 24.3333h;92%
With sulfuric acid; water In methanol at -5 - 20℃; for 26h;92%
3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

2-amino-benzenethiol
137-07-5

2-amino-benzenethiol

2-(2'-Hydroxy-3'-chlorophenyl)benzothiazole
90481-39-3

2-(2'-Hydroxy-3'-chlorophenyl)benzothiazole

Conditions
ConditionsYield
With phosphorus trichloride In toluene for 4h; Heating;94%
With phosphorus trichloride In toluene at 100℃;45%
2,2,2-trifluoroethanol
75-89-8

2,2,2-trifluoroethanol

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

C9H6ClF3O3

C9H6ClF3O3

Conditions
ConditionsYield
With thionyl chloride for 6h; Inert atmosphere; Reflux;82%
2-iodo-propane
75-30-9

2-iodo-propane

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

3-chloro-2-isopropoxybenzoic acid isopropyl ester
894851-25-3

3-chloro-2-isopropoxybenzoic acid isopropyl ester

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 70℃; for 66h;77%
3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

acetic anhydride
108-24-7

acetic anhydride

2-(acetylocy)-3-chlorobenzoic acid
16534-19-3

2-(acetylocy)-3-chlorobenzoic acid

Conditions
ConditionsYield
Stage #1: 3-Chloro-2-hydroxybenzoic acid; acetic anhydride With triethylamine In tetrahydrofuran at 20℃; for 22.5h;
Stage #2: With hydrogenchloride In water
76%
With sulfuric acid at 140℃; for 2h;43%
With sulfuric acid
With sulfuric acid In water at 20℃; Heating;
3-aminoquinoline
580-17-6

3-aminoquinoline

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

3-chloro-2-hydroxy-N-(quinolin-3-yl)benzamide
1257883-68-3

3-chloro-2-hydroxy-N-(quinolin-3-yl)benzamide

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 40℃; for 8h;76%
3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

1,2-diamino-benzene
95-54-5

1,2-diamino-benzene

2-(2'-Hydroxy-3'-chlorophenyl)benzimidazole
96459-82-4

2-(2'-Hydroxy-3'-chlorophenyl)benzimidazole

Conditions
ConditionsYield
With PPA at 150℃;75%
orcinol
504-15-4

orcinol

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

5-chloro-1-hydroxy-3-methyl-9H-xanthen-9-one

5-chloro-1-hydroxy-3-methyl-9H-xanthen-9-one

Conditions
ConditionsYield
With methanesulfonic acid; phosphorus pentoxide at 90℃;71%
2-(4-pyridylmethylene amino) ethanol
106782-22-3

2-(4-pyridylmethylene amino) ethanol

Cyclohexyl isocyanide
931-53-3

Cyclohexyl isocyanide

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

C22H26ClN3O4
917890-17-6

C22H26ClN3O4

Conditions
ConditionsYield
With 3 A molecular sieve In methanol at 20℃; Ugi reaction;64%
Cyclohexyl isocyanide
931-53-3

Cyclohexyl isocyanide

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

(E)-2-(benzylideneamino)ethanol
124948-51-2

(E)-2-(benzylideneamino)ethanol

C23H27ClN2O4
917890-16-5

C23H27ClN2O4

Conditions
ConditionsYield
With 3 A molecular sieve In methanol at 20℃; Ugi reaction;63%
3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

3,5-Bis-(trifluoromethyl)aniline
328-74-5

3,5-Bis-(trifluoromethyl)aniline

N-(3,5-bis-trifluoromethyl-phenyl)-3-chloro-2-hydroxy-benzamide

N-(3,5-bis-trifluoromethyl-phenyl)-3-chloro-2-hydroxy-benzamide

Conditions
ConditionsYield
With pyridine; phosphorus trichloride In toluene Inert atmosphere; Reflux;59%
With phosphorus trichloride In toluene Inert atmosphere; Reflux;24%
With phosphorus trichloride In 5,5-dimethyl-1,3-cyclohexadiene for 5h; Reflux;
3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

propyl bromide
106-94-5

propyl bromide

3-chloro-2-propoxybenzoic acid propyl ester
894851-30-0

3-chloro-2-propoxybenzoic acid propyl ester

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 30℃; for 66h;51%
3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

ethyl 2-amino-2,3-dihydro-1H-indene-2-carboxylate
141104-65-6

ethyl 2-amino-2,3-dihydro-1H-indene-2-carboxylate

2-(3-chloro-2-hydroxy-benzoylamino)-indan-2-carboxylic acid ethyl ester
1092447-22-7

2-(3-chloro-2-hydroxy-benzoylamino)-indan-2-carboxylic acid ethyl ester

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 20℃;49%
3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

methyl 3-((4-acetylpiperazin-1-yl)methyl)benzoate

methyl 3-((4-acetylpiperazin-1-yl)methyl)benzoate

methyl 3-((4-(8-chloro-4-oxochromen-2-yl)piperazin-1-yl)methyl)benzoate

methyl 3-((4-(8-chloro-4-oxochromen-2-yl)piperazin-1-yl)methyl)benzoate

Conditions
ConditionsYield
Stage #1: methyl 3-[(4-acetylpiperazin-1-yl)methyl]benzoate With trichlorophosphate In dichloromethane at 0 - 25℃; for 1h;
Stage #2: 3-Chloro-2-hydroxybenzoic acid In dichloromethane at 0 - 60℃; for 15h;
Stage #3: With sodium acetate In dichloromethane at 60℃; for 4h;
48.4%
C20H15N2PS2
89430-08-0

C20H15N2PS2

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

8-chloro-2-thioxo-2,3-dihydro-4H-1,3-benzoxazin-4-one

8-chloro-2-thioxo-2,3-dihydro-4H-1,3-benzoxazin-4-one

Conditions
ConditionsYield
In dichloromethane48%
tert-Octylamine
107-45-9

tert-Octylamine

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

3-chloro-2-hydroxy-N-(2,4,4-trimethylpentan-2-yl)benzamide

3-chloro-2-hydroxy-N-(2,4,4-trimethylpentan-2-yl)benzamide

Conditions
ConditionsYield
Stage #1: 3-Chloro-2-hydroxybenzoic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0℃; for 0.25h; Inert atmosphere;
Stage #2: tert-Octylamine In N,N-dimethyl-formamide at 0 - 20℃; for 16h;
43.08%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0 - 20℃; for 16h; Inert atmosphere;36.58%
perfluoro-2-methylpent-2-ene
1584-03-8

perfluoro-2-methylpent-2-ene

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

4-(F-ethyl)-3-(F-methyl)-10-chloro-2H,6H-1,5-benzodioxocin-2,6-dione

4-(F-ethyl)-3-(F-methyl)-10-chloro-2H,6H-1,5-benzodioxocin-2,6-dione

Conditions
ConditionsYield
With triethylamine In acetonitrile for 5h; Ambient temperature;41%
3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

diazomethyl-trimethyl-silane
18107-18-1

diazomethyl-trimethyl-silane

methyl 3-chloro-5-nitrosalicylate
337520-41-9

methyl 3-chloro-5-nitrosalicylate

Conditions
ConditionsYield
With sulfuric acid; nitric acid In methanol; hexane; benzene39%
3-nitro-5-(trifluoromethyl)-phenylamine
401-94-5

3-nitro-5-(trifluoromethyl)-phenylamine

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

3-chloro-2-hydroxy-N-(3-nitro-5-(trifluoromethyl)phenyl)benzamide

3-chloro-2-hydroxy-N-(3-nitro-5-(trifluoromethyl)phenyl)benzamide

Conditions
ConditionsYield
With phosphorus trichloride In 5,5-dimethyl-1,3-cyclohexadiene for 5h; Reflux;39%
3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

3-chloro-N-(3,5-dimethylphenyl)-2-hydroxybenzamide

3-chloro-N-(3,5-dimethylphenyl)-2-hydroxybenzamide

Conditions
ConditionsYield
With phosphorus trichloride In toluene Inert atmosphere; Reflux;27%
1-[4-(3-aminophenyl)piperazin-1-yl]-2-(5-methyl-3-trifluoromethylpyrazol-1-yl)ethanone
1392267-89-8

1-[4-(3-aminophenyl)piperazin-1-yl]-2-(5-methyl-3-trifluoromethylpyrazol-1-yl)ethanone

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

3-chloro-2-hydroxy-N-(3-{4-[2-(5-methyl-3-trifluoromethylpyrazol-1-yl)acetyl]piperazin-1-yl}phenyl)benzamide
1392267-90-1

3-chloro-2-hydroxy-N-(3-{4-[2-(5-methyl-3-trifluoromethylpyrazol-1-yl)acetyl]piperazin-1-yl}phenyl)benzamide

Conditions
ConditionsYield
Stage #1: 3-Chloro-2-hydroxybenzoic acid With 1,1'-carbonyldiimidazole In acetonitrile at 60℃; for 2h;
Stage #2: 1-[4-(3-aminophenyl)piperazin-1-yl]-2-(5-methyl-3-trifluoromethylpyrazol-1-yl)ethanone With 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 60℃;
26%
Stage #1: 3-Chloro-2-hydroxybenzoic acid With 1,1'-carbonyldiimidazole In acetonitrile at 60℃; for 2h;
Stage #2: 1-[4-(3-aminophenyl)piperazin-1-yl]-2-(5-methyl-3-trifluoromethylpyrazol-1-yl)ethanone With 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 60℃;
2-amino-6-bromobenzothiazole
15864-32-1

2-amino-6-bromobenzothiazole

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

3-chloro-N-(6-bromo-1,3-benzothiazol-2-yl)-2-hydroxybenzamide

3-chloro-N-(6-bromo-1,3-benzothiazol-2-yl)-2-hydroxybenzamide

Conditions
ConditionsYield
Stage #1: 3-Chloro-2-hydroxybenzoic acid With phosphorus trichloride In chlorobenzene for 0.5h; Reflux;
Stage #2: 2-amino-6-bromobenzothiazole In chlorobenzene for 4h; Reflux;
26%
(1R)-5-chloroindan-1-amine

(1R)-5-chloroindan-1-amine

3-Chloro-2-hydroxybenzoic acid
1829-32-9

3-Chloro-2-hydroxybenzoic acid

C16H13Cl2NO2

C16H13Cl2NO2

Conditions
ConditionsYield
With dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; for 12h;21%

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