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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem鈥檚 R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities of

3,5-Dimethylaniline

Cas:108-69-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 3,5-Xylidine(Nh2=1) supplier in China

Cas:108-69-0

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:Colorless liquid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

3,5-Dimethylaniline

Cas:108-69-0

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 3,5-xylidine

Cas:108-69-0

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3,5-Xylidine (NH2=1)

Cas:108-69-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

3,5-Dimethylaniline

Cas:108-69-0

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so

108-69-0 3,5-Dimethylaniline

Cas:108-69-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

3,5-Dimethylaniline

Cas:108-69-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Business Custom Synthesis: Trading(Raw Mater

3,5-Dimethylaniline

Cas:108-69-0

Min.Order:0 Metric Ton

FOB Price: $18.0 / 20.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

superior quality Appearance:Dark brown liquid. Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Used as Pharmaceutical Intermediates Transportation

3,5-Dimethylaniline

Cas:108-69-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

3,5-Dimethylaniline

Cas:108-69-0

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3,5-Dimethylaniline

Cas:108-69-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...)

3,5-DimethylanilineCAS NO.: 108-69-0

Cas:108-69-0

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Lab/Research institutions

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

ProductName:3,5-Dimethylaniline CAS:108-69-0 Molecular Formula:C8H11N Molecular Weight:121.18000 Appearance:Colorless to reddish brown liquid Assay:≥99.0% Water content:≤0.20% Appearance:brown liquid Storage:keep sealed an

3,5-Dimethylaniline

Cas:108-69-0

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

3,5-Dimethylaniline

Cas:108-69-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/3,5-Dimethylaniline

Cas:108-69-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Beijing Greenchem Technology Co.,Ltd. ( Panjin Greenchem Technology Co.Ltd .)

Capability on chemical synthesis1. Beijing High-Tech Enterprises2. Strong R&D Team3. 8 years of experiences in R & D of high-tech Catalyst;4. 5000 production techniques, 69 items of national patents, and 360 kinds of products on sales;5. The producti

3,5-Dimethylaniline

Cas:108-69-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Greenutra Resource Inc

3,5-DimethylanilineAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air

3,5-Dimethylaniline

Cas:108-69-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hubei Vanz Pharm Co.,Ltd

ISO/factory/goodqualityAppearance:off white Storage:Dry,cool place Package:drum Application:active pharmaceutical ingredients Transportation:by air/sea/express Port:shenzhen/shanghai

3,5-Dimethylaniline

Cas:108-69-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

3,5-Dimethylaniline

Cas:108-69-0

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

3,5-DiMethylaniline

Cas:108-69-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

3,5-Dimethylaniline

Cas:108-69-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Fortuna Chemical Co.,Ltd

1.High quality : the purity is 99% min . through multiple producing procedures. 2.Competitive price : low price because of our skilled production technolpgy ,save the production cost at most , and give big profit room to our customers330.Safe and fa

3,5-Dimethylaniline

Cas:108-69-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

3,5-Xylidine(Nh2=1)

Cas:108-69-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

Product Description Description & Specification Category Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug Standard Medical standard

factory supply CAS 108-69-0 with competitive price

Cas:108-69-0

Min.Order:1 Kilogram

FOB Price: $112.0

Type:Trading Company

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

3,5-DiMethylaniline

Cas:108-69-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Ocean Chemical Co., Ltd.

★.Best quality according to requirement ★.Competitive price in China market ★.Mature Technical support ★.Professional logistic support

3,5-Dimethylaniline

Cas:108-69-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

3,5-Dimethylaniline, 98% Application:3,5-Dimethylaniline, 98%

3,5-Dimethylaniline, 98%

Cas:108-69-0

Min.Order:0

Negotiable

Type:Other

inquiry

Hunan Longxianng Runhui Trading Co.,Ltd

3,5-Dimethylaniline, 98%Appearance:White powder Storage:Room temperature Package:25KG/drum Application:Organic chemicals Transportation:By express (Door to door) such as FEDEX, DHL, EMS for small amount. By air(airport to airport) or by sea LCL/FCL f

3,5-Dimethylaniline, 98%

Cas:108-69-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

3,5-Dimethylaniline 108-69-0

Cas:108-69-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

5-bromo-1,3-xylene
556-96-7

5-bromo-1,3-xylene

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
With copper(I) oxide; ammonium hydroxide In 1-methyl-pyrrolidin-2-one at 80℃; for 15h;100%
With copper(l) iodide; 2-carboxyquinoline N-oxide; potassium carbonate; ammonium hydroxide In dimethyl sulfoxide at 80℃; for 23h; Inert atmosphere;91%
With copper(l) iodide; ammonia; sodium phosphate In water at 100℃; for 24h;86%
With diethylenetriaminopentaacetic acid; ammonia; copper(II) oxide; potassium hydroxide In water at 100℃; for 6h;74%
Stage #1: 5-bromo-1,3-xylene With magnesium In tetrahydrofuran Inert atmosphere;
Stage #2: With C10H17NO In tetrahydrofuran; toluene at -78℃; for 2h; Inert atmosphere;
Stage #3: With ammonium chloride In tetrahydrofuran; water; toluene Inert atmosphere;
74%
5-nitro-m-xylene
99-12-7

5-nitro-m-xylene

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
With borane-ammonia complex In methanol; water at 49.84℃; for 0.166667h; Catalytic behavior;99%
With sodium tetrahydroborate In water at 60℃; for 0.0166667h;96%
Stage #1: 5-nitro-m-xylene With Cu(OH)x impregnated on Fe3O4 In water for 0.0833333h; Green chemistry;
Stage #2: With sodium tetrahydroborate In water at 55 - 60℃; for 0.116667h; Green chemistry;
95%
3,5-dimethylphenyl iodide
22445-41-6

3,5-dimethylphenyl iodide

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
With copper(I) oxide; ammonium hydroxide In 1-methyl-pyrrolidin-2-one at 80℃; for 15h;99%
With potassium phosphate; copper(l) iodide; N-((1-oxy-pyridin-2-yl)methyl)oxalamic acid; ammonia In water; dimethyl sulfoxide at 25℃; Schlenk technique; Inert atmosphere; Sealed tube; chemoselective reaction;95%
With copper(l) iodide; 2-carboxyquinoline N-oxide; potassium carbonate; ammonium hydroxide In dimethyl sulfoxide at 50℃; for 23h; Inert atmosphere;92%
1-chloro-3,5-dimethylbenzene
556-97-8

1-chloro-3,5-dimethylbenzene

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
With ammonium hydroxide; potassium phosphate In dimethyl sulfoxide at 80℃; UV-irradiation;99%
Multi-step reaction with 2 steps
1.1: sulfuric acid; nitric acid / 30 °C / Cooling with ice
2.1: palladium on activated charcoal / ethanol / 0.5 h / 50 °C / Autoclave
2.2: 0.83 h / 65 °C / 2250.23 Torr / Autoclave
View Scheme
N-hydroxy-3,5-dimethylbenzamide
62034-72-4

N-hydroxy-3,5-dimethylbenzamide

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
With potassium carbonate In dimethyl sulfoxide at 90℃; for 4h; Lossen Rearrangement;97%
3,5-Dimethylphenol
108-68-9

3,5-Dimethylphenol

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
With palladium/alumina; ammonia; hydrogen In toluene at 250℃; under 2250.23 Torr; Temperature; Pressure; Solvent;95%
With 5%-palladium/activated carbon; hydrazine hydrate; lithium hydroxide In 1,4-dioxane at 170℃; for 16h; Molecular sieve; Inert atmosphere;71%
With ammonia at 350℃; under 117681 - 183877 Torr;
With aluminum oxide; nitrogen; ammonia; hydrogen at 450℃; under 147102 Torr;
3,5-dimethyl-cyclohexanone oxime
101252-04-4

3,5-dimethyl-cyclohexanone oxime

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
With Pd(OH)x/LDH In N,N-dimethyl acetamide at 130℃; for 11h; Schlenk technique; Inert atmosphere;91%
5-[(3,5-dimethylphenyl)imino]-5H-5γ4-dibenzo[b,d]thiophene-5-oxide

5-[(3,5-dimethylphenyl)imino]-5H-5γ4-dibenzo[b,d]thiophene-5-oxide

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
With 2,2'-azobis(isobutyronitrile); tris-(trimethylsilyl)silane In toluene at 100℃; Sealed tube;88%
1,2,3,4-tetrahydroisoquinoline
635-46-1

1,2,3,4-tetrahydroisoquinoline

5-nitro-m-xylene
99-12-7

5-nitro-m-xylene

A

quinoline
91-22-5

quinoline

B

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
With nickel-nitrogen-doped carbon framework In water at 145℃; for 18h; Inert atmosphere; Sealed tube; Green chemistry;A 73%
B 76%
5-nitro-m-xylene
99-12-7

5-nitro-m-xylene

2-methyl indoline
6872-06-6

2-methyl indoline

A

2-methyl-1H-indole
95-20-5

2-methyl-1H-indole

B

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
With nickel-nitrogen-doped carbon framework In water at 145℃; for 18h; Inert atmosphere; Sealed tube; Green chemistry;A 74%
B 76%
3,5-dimethylcyclohexanone
2320-30-1

3,5-dimethylcyclohexanone

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
With ethene; 5%-palladium/activated carbon; ammonium acetate In acetonitrile at 90℃; under 760.051 Torr; for 15h; Schlenk technique;71%
ethanol
64-17-5

ethanol

5-nitro-m-xylene
99-12-7

5-nitro-m-xylene

A

2,5,7-trimethylquinoline
102871-67-0

2,5,7-trimethylquinoline

B

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
With platinum-loaded TiO2 at 30℃; for 5h; UV-irradiation;A 68%
B 16%
2,4-Xylenol
105-67-9

2,4-Xylenol

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
Stage #1: 2,4-Xylenol With Nonafluorobutanesulfonyl fluoride; tris(trimethylsilyl)amine; potassium hexamethylsilazane In tetrahydrofuran at 60℃; for 5h; Schlenk technique; Inert atmosphere;
Stage #2: With hydrogenchloride In water at 20℃; for 0.0833333h; pH=3 - 4;
67%
5-methoxyindoline
21857-45-4

5-methoxyindoline

5-nitro-m-xylene
99-12-7

5-nitro-m-xylene

A

5-methoxylindole
1006-94-6

5-methoxylindole

B

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
With nickel-nitrogen-doped carbon framework In water at 145℃; for 18h; Inert atmosphere; Sealed tube; Green chemistry;A 62%
B 61%
m-xylene
108-38-3

m-xylene

A

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

B

2,4-Xylidine
95-68-1

2,4-Xylidine

C

2,6-dimethylaniline
87-62-7

2,6-dimethylaniline

Conditions
ConditionsYield
With tris-(2-chloro-ethyl)-amine; trifluorormethanesulfonic acid; trifluoroacetic acid In chloroform at 25℃; for 1h;A 2%
B 58%
C 15%
With hydrogenchloride; aluminium trichloride; sodium azide In various solvent(s) at 20℃;
With sodium azide; trifluorormethanesulfonic acid at 20℃; Ultrasonic irradiation;
Stage #1: m-xylene With sulfuric acid; hydroxylamine hydrochloride In acetonitrile at 25℃; for 0.166667h;
Stage #2: With hydrogenchloride; titanium(III) chloride In water; acetonitrile at 25℃; Inert atmosphere; Sealed tube; Overall yield = 60 percent; Overall yield = 72 mg;
3,5-dimethylbenzoic acid
499-06-9

3,5-dimethylbenzoic acid

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
With hydrogenchloride; PPA; hydroxylamine
3,5-dimethylbenzamide
5692-35-3

3,5-dimethylbenzamide

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
With alkaline sodium hypobromite
2-amino-4,6-dimethylbenzene-1,3-dicarbonitrile
10272-10-3

2-amino-4,6-dimethylbenzene-1,3-dicarbonitrile

A

2-amino-4,6-dimethyl benzamide
875241-52-4

2-amino-4,6-dimethyl benzamide

B

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
With sulfuric acid
3,5-dimethyl-cyclohex-2-enone oxime
67543-92-4

3,5-dimethyl-cyclohex-2-enone oxime

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
With hydrogenchloride at 170℃;
3,5-Dimethylphenol
108-68-9

3,5-Dimethylphenol

A

bis-(3,5-dimethylphenyl)-amine
5369-25-5

bis-(3,5-dimethylphenyl)-amine

B

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
With ammonium chloride at 350℃; under 36775.4 Torr;
5-nitro-m-xylene

5-nitro-m-xylene

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
With hydrogenchloride; tin(ll) chloride
With iron; acetic acid
With hydrogenchloride; tin
ammonia
7664-41-7

ammonia

3,5-Dimethylphenol
108-68-9

3,5-Dimethylphenol

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
at 350℃; under 117681 Torr;
ammonium chloride

ammonium chloride

3,5-Dimethylphenol
108-68-9

3,5-Dimethylphenol

A

bis-(3,5-dimethylphenyl)-amine
5369-25-5

bis-(3,5-dimethylphenyl)-amine

B

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
at 350℃; under 36775.4 - 44130.5 Torr;
3,5-dimethylbenzamide
5692-35-3

3,5-dimethylbenzamide

alkaline hypobromite

alkaline hypobromite

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

1,2,3-triethylbenzene
42205-08-3

1,2,3-triethylbenzene

bis-(3,5-dimethyl-cyclohex-2-enylidene)-hydrazine
83186-90-7

bis-(3,5-dimethyl-cyclohex-2-enylidene)-hydrazine

palladium/charcoal

palladium/charcoal

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

hydrogenchloride
7647-01-0

hydrogenchloride

4-(3,5-dimethyl-phenylazo)-3,5-dimethyl-aniline
91536-77-5

4-(3,5-dimethyl-phenylazo)-3,5-dimethyl-aniline

tin

tin

A

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

B

2.5-diamino-m-xylene

2.5-diamino-m-xylene

[Pd((CH3)2C6H3NH2)4](2+)*2CF3COCHCOCF3(1-)=[Pd((CH3)2C6H3NH2)4](CF3COCHCOCF3)2

[Pd((CH3)2C6H3NH2)4](2+)*2CF3COCHCOCF3(1-)=[Pd((CH3)2C6H3NH2)4](CF3COCHCOCF3)2

[Pd(CF3COCHCOCF3)((CH3)2C6H3NH2)2](1+)*CF3COCHCOCF3(1-)=[Pd(CF3COCHCOCF3)((CH3)2C6H3NH2)2](CF3COCHCOCF3)

[Pd(CF3COCHCOCF3)((CH3)2C6H3NH2)2](1+)*CF3COCHCOCF3(1-)=[Pd(CF3COCHCOCF3)((CH3)2C6H3NH2)2](CF3COCHCOCF3)

B

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
In chloroform-d1 not isolated; detected by NMR;
(E)-cyclooct-2-en-1-yl (3,5-dimethylphenyl)carbamate

(E)-cyclooct-2-en-1-yl (3,5-dimethylphenyl)carbamate

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
With 3,6-dimethyl-1,2,4,5-tetrazine; formic acid In acetonitrile at 20℃; for 1h; Reagent/catalyst; Solvent;
With 3,6-dimethyl-1,2,4,5-tetrazine; formic acid In acetonitrile at 20℃; for 1h; Reagent/catalyst; Solvent;
3,6-dimethyl-1,2,4,5-tetrazine
1558-23-2

3,6-dimethyl-1,2,4,5-tetrazine

C17H23NO2

C17H23NO2

A

C12H18N2
86997-05-9

C12H18N2

B

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Conditions
ConditionsYield
With pyridine In acetonitrile at 20℃; for 1h; Reagent/catalyst;
3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

N-(3,5-dimethylphenyl)-4-methyl-benzenesulfonamide
114097-28-8

N-(3,5-dimethylphenyl)-4-methyl-benzenesulfonamide

Conditions
ConditionsYield
With triethylamine In dichloromethane at 4℃;100%
With silica gel at 20℃;95%
With triethylamine In dichloromethane at 0 - 20℃;82%
3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

Trimethylacetic acid
75-98-9

Trimethylacetic acid

N-(3,5-dimethylphenyl)pivalamide
86489-67-0

N-(3,5-dimethylphenyl)pivalamide

Conditions
ConditionsYield
With diphosphorus tetraiodide In tetrachloromethane; dichloromethane Heating;100%
3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

dimethyl acetylenedicarboxylate
762-42-5

dimethyl acetylenedicarboxylate

dimethyl (Z)-N-(3,5-dimethylphenyl)aminofumarate
92952-51-7

dimethyl (Z)-N-(3,5-dimethylphenyl)aminofumarate

Conditions
ConditionsYield
at 20℃; for 0.133333h; Michael addition;100%
In diethyl ether at 0℃;75%
4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

3,5-dimethyl-N-(4-methoxybenzylidene)aniline
199435-31-9

3,5-dimethyl-N-(4-methoxybenzylidene)aniline

Conditions
ConditionsYield
at 20℃;100%
With acetic acid In methanol at 20℃;
Ethyl oxalyl chloride
4755-77-5

Ethyl oxalyl chloride

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

2-(3,5-dimethylphenylamino)-2-oxoacetic acidethyl ester
333441-77-3

2-(3,5-dimethylphenylamino)-2-oxoacetic acidethyl ester

Conditions
ConditionsYield
With pyridine at 20℃; for 1.5h; Inert atmosphere;100%
With triethylamine In tetrahydrofuran at 0 - 20℃;68%
3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

3-(3,5-dimethyl-phenylamino)-propionamide
857070-85-0

3-(3,5-dimethyl-phenylamino)-propionamide

Conditions
ConditionsYield
With ammonia In methanol at 80℃;100%
2-(2-tert-butoxycarbonylaminopyridin-4-ylmethylthio)pyridine-3-carboxylic acid
864460-87-7

2-(2-tert-butoxycarbonylaminopyridin-4-ylmethylthio)pyridine-3-carboxylic acid

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

2-(2-tert-Butoxycarbonylaminopyridin-4-ylmethylthio)-N-(3,5-dimethylphenyl)pyridine-3-carboxamide

2-(2-tert-Butoxycarbonylaminopyridin-4-ylmethylthio)-N-(3,5-dimethylphenyl)pyridine-3-carboxamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 20℃; for 12h;100%
{4-[6-formyl-1-(3-hydroxy-6-methylpyridin-2-ylmethyl)-1H-benzoimidazol-2-ylamino]piperidin-1-yl}acetic acid ethyl ester
1009646-49-4

{4-[6-formyl-1-(3-hydroxy-6-methylpyridin-2-ylmethyl)-1H-benzoimidazol-2-ylamino]piperidin-1-yl}acetic acid ethyl ester

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

{4-[6-[(3,5-dimethylphenylamino)methyl]-1-(3-hydroxy-6-methylpyridin-2-ylmethyl)-1H-benzoimidazol-2-ylamino]piperidin-1-yl}acetic acid ethyl ester
1009646-54-1

{4-[6-[(3,5-dimethylphenylamino)methyl]-1-(3-hydroxy-6-methylpyridin-2-ylmethyl)-1H-benzoimidazol-2-ylamino]piperidin-1-yl}acetic acid ethyl ester

Conditions
ConditionsYield
With sodium cyanoborohydride; acetic acid In acetonitrile at 20℃; for 12h;100%
3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

1,2-dibromobenzene
583-53-9

1,2-dibromobenzene

N,N'-di(3,5-dimethylphenyl)benzene-1,2-diamine
1068437-89-7

N,N'-di(3,5-dimethylphenyl)benzene-1,2-diamine

Conditions
ConditionsYield
With ammonium chloride; sodium t-butanolate; palladium diacetate In water; argon; toluene100%
With tri-tert-butyl phosphine; palladium diacetate; sodium t-butanolate In toluene at 110℃; for 14h; Inert atmosphere;100 %Chromat.
β-(1-naphthyl)nitroethylene
37630-26-5, 4735-49-3

β-(1-naphthyl)nitroethylene

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

C20H20N2O2
1268482-47-8

C20H20N2O2

Conditions
ConditionsYield
at 20℃; for 0.1h; Michael addition; neat (no solvent);100%
1-nitro-2-(2-nitrovinyl)benzene
5670-66-6, 5670-67-7, 3156-39-6

1-nitro-2-(2-nitrovinyl)benzene

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

C16H17N3O4
1268482-40-1

C16H17N3O4

Conditions
ConditionsYield
at 20℃; for 0.1h; Michael addition; neat (no solvent);100%
(2-nitroethenyl)benzene
102-96-5

(2-nitroethenyl)benzene

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

C16H18N2O2
1266995-18-9

C16H18N2O2

Conditions
ConditionsYield
at 20℃; for 0.1h; Michael addition; neat (no solvent);100%
3-nitro-β-nitrostyrene
882-26-8

3-nitro-β-nitrostyrene

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

3,5-dimethyl-N-[2-nitro-1-(3-nitro-phenyl)-ethyl]-aniline
108836-94-8

3,5-dimethyl-N-[2-nitro-1-(3-nitro-phenyl)-ethyl]-aniline

Conditions
ConditionsYield
at 20℃; for 0.1h; Michael addition; neat (no solvent);100%
1-chloro-4-(2-nitrovinyl)benzene
706-07-0

1-chloro-4-(2-nitrovinyl)benzene

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

C16H17ClN2O2
1268482-45-6

C16H17ClN2O2

Conditions
ConditionsYield
at 20℃; for 0.1h; Michael addition; neat (no solvent);100%
3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

acetylenedicarboxylic acid diethyl ester
762-21-0

acetylenedicarboxylic acid diethyl ester

diethyl (Z)-N-(3,5-dimethylphenyl)aminofumarate
1349802-62-5

diethyl (Z)-N-(3,5-dimethylphenyl)aminofumarate

Conditions
ConditionsYield
at 20℃; for 0.15h; Michael addition;100%
benzaldehyde
100-52-7

benzaldehyde

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

3,5-dimethyl-N-benzylideneaniline
91000-43-0

3,5-dimethyl-N-benzylideneaniline

Conditions
ConditionsYield
at 20℃;100%
In methanol99%
In ethanol for 3h; Reflux;
4-methyl-benzaldehyde
104-87-0

4-methyl-benzaldehyde

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

3,5-dimethyl-N-(4-methylbenzylidene)aniline
107399-20-2

3,5-dimethyl-N-(4-methylbenzylidene)aniline

Conditions
ConditionsYield
at 20℃;100%
4-chlorobenzaldehyde
104-88-1

4-chlorobenzaldehyde

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

3,5-dimethyl-N-(4-chlorobenzylidene)aniline
180569-73-7

3,5-dimethyl-N-(4-chlorobenzylidene)aniline

Conditions
ConditionsYield
at 20℃;100%
In neat (no solvent) at 20℃; for 0.5h; Schlenk technique; Molecular sieve; Inert atmosphere;
3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

4-bromo-benzaldehyde
1122-91-4

4-bromo-benzaldehyde

3,5-dimethyl-N-(4-bromobenzylidene)aniline
348601-49-0

3,5-dimethyl-N-(4-bromobenzylidene)aniline

Conditions
ConditionsYield
at 20℃;100%
Isophthalaldehyde
626-19-7

Isophthalaldehyde

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

C24H26N2

C24H26N2

Conditions
ConditionsYield
at 20℃;100%
2-bromo-butyryl bromide
26074-52-2

2-bromo-butyryl bromide

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

2-bromo-N-(3,5-dimethylphenyl)butanamide

2-bromo-N-(3,5-dimethylphenyl)butanamide

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;100%
3-Hydroxy-3-methylbutyric acid
625-08-1

3-Hydroxy-3-methylbutyric acid

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

C13H19NO2

C13H19NO2

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 14h;100%
acetic anhydride
108-24-7

acetic anhydride

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

N-acetyl-3,5-dimethylaniline
2050-45-5

N-acetyl-3,5-dimethylaniline

Conditions
ConditionsYield
In tetrahydrofuran at 0 - 20℃; Inert atmosphere;99%
Stage #1: acetic anhydride; 3,5-dimethylaminoaniline In tetrahydrofuran at 0 - 20℃; Inert atmosphere;
Stage #2: With sodium hydroxide In tetrahydrofuran; water pH=12 - 14; Cooling with ice;
99%
Stage #1: acetic anhydride; 3,5-dimethylaminoaniline In tetrahydrofuran at 20℃; for 1h; Inert atmosphere;
Stage #2: With sodium hydroxide In tetrahydrofuran; water pH=12 - 14; Cooling with ice;
99%
3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

acetyl chloride
75-36-5

acetyl chloride

N-acetyl-3,5-dimethylaniline
2050-45-5

N-acetyl-3,5-dimethylaniline

Conditions
ConditionsYield
With triethylamine In dichloromethane at 201℃; for 1h;99%
Stage #1: 3,5-dimethylaminoaniline With potassium carbonate In dichloromethane at 0℃; for 0.5h; Inert atmosphere;
Stage #2: acetyl chloride for 2h; Inert atmosphere;
99%
With potassium carbonate In dichloromethane at 20℃; for 2.5h; Cooling with ice;98.8%
4-hydroxyphenylacetate
156-38-7

4-hydroxyphenylacetate

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

N-(3,5-dimethylphenyl)-4-hydroxyphenylacetamide
131179-77-6

N-(3,5-dimethylphenyl)-4-hydroxyphenylacetamide

Conditions
ConditionsYield
With fluorosulfonyl fluoride; N-ethyl-N,N-diisopropylamine In acetonitrile at 20℃; for 5h;99%
With boric acid In toluene for 18h; Heating;95%
With pyridine; FI-750-M; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In water at 60℃; for 0.75h; Sealed tube;86%
2-dimethylaminomethylene-1,3-bis(dimethylimonio)propane diperchlorate
2009-81-6

2-dimethylaminomethylene-1,3-bis(dimethylimonio)propane diperchlorate

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

3-(3,5-dimethylphenylamino)-2-(dimethylphenyliminomethyl)propenal hydrogenperchlorate

3-(3,5-dimethylphenylamino)-2-(dimethylphenyliminomethyl)propenal hydrogenperchlorate

Conditions
ConditionsYield
With perchloric acid In ethanol at 105℃; for 1.5h;99%
1-(tert-butoxycarbonyl)-L-proline
15761-39-4

1-(tert-butoxycarbonyl)-L-proline

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

(S)-tert-butyl 2-((3,5-dimethylphenyl)carbamoyl)pyrrolidine-1-carboxylate
137496-70-9

(S)-tert-butyl 2-((3,5-dimethylphenyl)carbamoyl)pyrrolidine-1-carboxylate

Conditions
ConditionsYield
With chloroformic acid ethyl ester; triethylamine In dichloromethane at 20℃; for 1h;99%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 12h;85%
With benzotriazol-1-ol; dicyclohexyl-carbodiimide In dichloromethane for 12h; Ambient temperature;65%
para-chlorotoluene
106-43-4

para-chlorotoluene

3,5-dimethylaminoaniline
108-69-0

3,5-dimethylaminoaniline

3,5-dimethyl-N-p-tolylbenzenamine
34160-16-2

3,5-dimethyl-N-p-tolylbenzenamine

Conditions
ConditionsYield
With bis(η3-allyl-μ-chloropalladium(II)); potassium tert-butylate; 1,3-bis[(2,6-diisopropyl)phenyl]imidazolinium chloride In 1,4-dioxane at 100℃; for 1.5h; Inert atmosphere;99%
With bis[chloro(1,2,3-trihapto-allylbenzene)palladium(II)]; N-[2-(di(1-adamantyl)phosphino)phenyl]morpholine; potassium hydroxide; sodium t-butanolate In water at 110℃; for 22h; Buchwald-Hartwig amination; Inert atmosphere; chemoselective reaction;95%
With sodium t-butanolate; [Na2PdCl4]; dicyclohexyl-(9-ethyl-9H-fluoren-9-yl)phosphane*HBF4 In toluene at 120℃; for 12h; Buchwald-Hartwig coupling reaction;
With sodium t-butanolate; palladium diacetate; dicyclohexyl(9-ethyl-9H-fluorene-9-yl)-phosphine·HBF4 In toluene at 120℃; for 12h; Product distribution / selectivity; Buchwald-Hartwig Amination;

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