1420987-86-5 Usage
Description
1,4-di(benzo[b]thiophen-4-yl)piperazine, also known as B677385, is a chemical compound that serves as an impurity in the drug Brexpiprazole. 1,4-di(benzo[b]thiophen-4-yl)piperazine is characterized by its unique molecular structure, which features two benzo[b]thiophen-4-yl groups attached to a central piperazine ring. Its chemical properties and interactions with other molecules make it a significant component in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
1,4-di(benzo[b]thiophen-4-yl)piperazine is used as an impurity in the drug Brexpiprazole for the treatment and prevention of mental disorders, particularly those affecting the central nervous system (CNS). Brexpiprazole is a drug candidate that has shown promise in managing various mental health conditions, and the presence of this compound as an impurity may influence the drug's overall efficacy and safety profile.
As an impurity in Brexpiprazole, 1,4-di(benzo[b]thiophen-4-yl)piperazine plays a role in the development and formulation of the drug. It is essential to monitor and control the levels of this impurity to ensure the safety and effectiveness of Brexpiprazole in treating CNS disorders and other mental health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1420987-86-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,0,9,8 and 7 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1420987-86:
(9*1)+(8*4)+(7*2)+(6*0)+(5*9)+(4*8)+(3*7)+(2*8)+(1*6)=175
175 % 10 = 5
So 1420987-86-5 is a valid CAS Registry Number.
1420987-86-5Relevant articles and documents
METHOD FOR PRODUCING BENZO[B]THIOPHENE COMPOUND
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, (2013/03/26)
The present invention provides a method for producing a compound of Formula (4): wherein R1 is a hydrogen atom etc. by reacting a compound of Formula (2): wherein X1 is a leaving group, with a compound of Formula (3): wherein R1 is as defined above, in the presence of (a) a palladium compound and a tertiary phosphine or (b) a palladium carbene complex, in an inert solvent or without a solvent. The present invention can produce the compound of Formula (4), with high purity and high yield, and by a simple operation.
