1422275-80-6

Basic information

• Product Name: ethyl {2-amino-5-bromo-6-[(4-fluorobenzyl)amino]-pyridin-3-yl}carbamate
• Synonyms: ethyl {2-amino-5-bromo-6-[(4-fluorobenzyl)amino]-pyridin-3-yl}carbamate
• CAS NO: 1422275-80-6
• Molecular Weight: 383.22
• Mol File: 1422275-80-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl {2-amino-5-bromo-6-[(4-fluorobenzyl)amino]-pyridin-3-yl}carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl {2-amino-5-bromo-6-[(4-fluorobenzyl)amino]-pyridin-3-yl}carbamate(1422275-80-6)
• EPA Substance Registry System: ethyl {2-amino-5-bromo-6-[(4-fluorobenzyl)amino]-pyridin-3-yl}carbamate(1422275-80-6)

Safety Data

• Hazardous Substances Data: 1422275-80-6(Hazardous Substances Data)

Upstream product

• 33400-49-6 2-amino-3-nitro-6-(p-fluoro-benzylamino)-pyridine 
• 140-75-0 para-fluorobenzylamine 
• 27048-04-0 2-amino-6-chloro-3-nitropyridine 
• 1422275-79-3 C₁₂H₁₂BrFN₄ 
• 541-41-3 chloroformic acid ethyl ester 

Downstream Products

• 1417916-52-9 diethyl {6,6'-diamino-2,2'-bis[(4-fluorobenzyl)amino]-3,3'-bipyridine-5,5'-diyl}biscarbamate 

Relevant articles and documents

Isolation, structure, synthesis and cytotoxicity of an unprecedented flupirtine dimer

A previously unknown dimer of the well-established analgesic flupirtine has been found, and its structure was revealed by ESI-MS, NMR spectroscopy and an independent synthesis. Thus, starting from 2-amino-6-chloro-3-nitro-pyridine the target compound was obtained in a four-step synthesis. Key-step of this synthesis is a nickel-mediated aryl-aryl coupling. The dimer 4 did not show any cytotoxicity, and its IC50 values were > 30 μm for all six human cancer cell lines and mouse fibroblasts used in this study.