142284-23-9Relevant articles and documents
Imino 1,2,3,4-tetrahydrocyclopent[b]indole carbamates as dual inhibitors of acetylcholinesterase and monoamine oxidase
Fink, David M.,Palermo,Bores, Gina M.,Huger, Francis P.,Kurys, Barbara E.,Merriman, Michael C.,Olsen, Gordon E.,Petko, Wayne,O'Malley, Gerard J.
, p. 625 - 630 (1996)
A series of imino 1,2,3,4-tetrahydrocyclopent[b]indole carbamates was prepared and evaluated as dual acetylcholinesterase (AChE) and monoamine oxidase (MAO) inhibitors. Halogen substitution ortho to the carbamate functionality in the eight position resulted in a significant increase in binding affinity for both AChE and MAO-A.