1424343-82-7

Basic information

• Product Name: N-(5-fluoro-2-iodophenyl)-3,4-dimethoxybenzamide
• Synonyms: N-(5-fluoro-2-iodophenyl)-3,4-dimethoxybenzamide
• CAS NO: 1424343-82-7
• Molecular Weight: 401.176
• Mol File: 1424343-82-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(5-fluoro-2-iodophenyl)-3,4-dimethoxybenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-fluoro-2-iodophenyl)-3,4-dimethoxybenzamide(1424343-82-7)
• EPA Substance Registry System: N-(5-fluoro-2-iodophenyl)-3,4-dimethoxybenzamide(1424343-82-7)

Safety Data

• Hazardous Substances Data: 1424343-82-7(Hazardous Substances Data)

Upstream product

• 3535-37-3 3,4-dimethoxybenzoic acid chloride 
• 255724-71-1 5-fluoro-2-iodoaniline 

Downstream Products

• 872726-44-8 NSC 721648 

Relevant articles and documents

Cu-catalyzed in situ generation of thiol using xanthate as a thiol surrogate for the one-pot synthesis of benzothiazoles and benzothiophenes

A new copper-catalyzed in situ generation of aryl thiolates strategy was successfully developed for the one-pot synthesis of substituted benzothiazoles from 2-iodoanilides using xanthate as a thiol precursor. A wide range of 2-iodoanilides with both electron-releasing and electron-withdrawing groups produced the corresponding benzothiazoles in good yields. Further, this one-pot protocol was successfully utilized for the synthesis of a potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzo[d]thiazole (PMX 610). Finally, the copper-catalyzed in situ generation of aryl thiolates strategy was successfully applied for the domino synthesis of substituted benzothiophenes from o-haloalkynyl benzenes using xanthate as a thiol precursor.