1427218-41-4

Basic information

• Product Name: ethyl 1-(4-bromophenyl)-3-oxoisoindoline-1-carboxylate
• Synonyms: ethyl 1-(4-bromophenyl)-3-oxoisoindoline-1-carboxylate
• CAS NO: 1427218-41-4
• Molecular Weight: 360.207
• Mol File: 1427218-41-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 1-(4-bromophenyl)-3-oxoisoindoline-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-(4-bromophenyl)-3-oxoisoindoline-1-carboxylate(1427218-41-4)
• EPA Substance Registry System: ethyl 1-(4-bromophenyl)-3-oxoisoindoline-1-carboxylate(1427218-41-4)

Safety Data

• Hazardous Substances Data: 1427218-41-4(Hazardous Substances Data)

Upstream product

• 61650-22-4 N-(pivaloyloxy)benzamide 
• 758692-47-6 ethyl α-diazo-α-(4-bromophenyl)acetate 

Relevant articles and documents

A coupling of benzamides and donor/acceptor diazo compounds to form γ-lactams via Rh(III)-catalyzed C-H activation

The coupling of O-pivaloyl benzhydroxamic acids with donor/acceptor diazo compounds provides isoindolones in high yield. The reaction tolerates a broad range of benzhydroxamic acids and diazo compounds, including substituted 2,2,2-trifluorodiazoethanes. Mechanistic experiments suggested that C-H activation is turnover-limiting and irreversible and that insertion of the diazo compound favors electron-deficient substrates.