14273-85-9 Usage
Description
METHYL 4-IODOBUTYRATE is an organic compound that can be synthesized from methyl-4-chlorobutyrate and sodium iodide. It is a reagent used in the synthesis of various organic compounds, particularly in the field of pharmaceuticals and biochemistry.
Uses
Used in Pharmaceutical Industry:
METHYL 4-IODOBUTYRATE is used as a reagent for the synthesis of 4-[formyl-5-(methoxymethyl)-1H-pyrrol-1-yl] butanoic acid, which is an important intermediate in the development of pharmaceutical compounds.
Used in Biochemical Research:
METHYL 4-IODOBUTYRATE is used in the synthesis of a range of stable S-adenosylmethionine (SAM) mimetics. These mimetics are valuable tools in studying the role of SAM in various biological processes and have potential applications in the development of new drugs and therapies.
Used in Molecular Biology:
The ability of METHYL 4-IODOBUTYRATE-derived compounds to promote the binding of the E. coli methionine repressor (MetJ) to its operator DNA has been investigated. This research contributes to the understanding of gene regulation mechanisms and can potentially lead to the development of novel strategies for controlling gene expression in various organisms.
Check Digit Verification of cas no
The CAS Registry Mumber 14273-85-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,2,7 and 3 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 14273-85:
(7*1)+(6*4)+(5*2)+(4*7)+(3*3)+(2*8)+(1*5)=99
99 % 10 = 9
So 14273-85-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H9IO2/c1-8-5(7)3-2-4-6/h2-4H2,1H3
14273-85-9Relevant articles and documents
Synthetic Methods and Reactions; 107. Preparation of ω-Haloalkylcarboxylic Acids and Esters or Related Compounds from Lactones and Boron Trihalides
Olah, George A.,Karpeles, Richard,Narang, Subhash C.
, p. 963 - 965 (1982)
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Visible-Light-Induced Nickel-Catalyzed Cross-Coupling with Alkylzirconocenes from Unactivated Alkenes
Bai, Songlin,Gao, Yadong,Jiang, Chao,Liu, Xiaolei,Qi, Xiangbing,Wang, Jing,Wu, Qingcui,Yang, Chao
supporting information, p. 675 - 688 (2020/03/11)
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Phosphorothioic acids and related compounds as surrogates for H 2S-synthesis of chiral tetrahydrothiophenes
Robertson, Forest J.,Wu, Jimmy
supporting information; experimental part, p. 2775 - 2780 (2012/03/22)
The convenient preparation of chiral tetrahydrothiophenes (THTs) in high enantiopurity via phosphorothioic acids and related compounds is reported. We consider these to be safer alternatives to the use of H2S which is a highly toxic gas. Each o
