216168-59-1Relevant articles and documents
Discovery of novel phenolic antioxidants as inhibitors of vascular cell adhesion molecule-1 expression for use in chronic inflammatory diseases
Meng, Charles Q.,Somers, Patricia K.,Hoong, Lee K.,Zheng, X. Sharon,Ye, Zhihong,Worsencroft, Kimberly J.,Simpson, Jacob E.,Hotema, Martha R.,Weingarten, M. David,MacDonald, Mathew L.,Hill, Russell R.,Marino, Elaine M.,Suen, Ki-Ling,Luchoomun, Jayraz,Kunsch, Charles,Landers, Laura K.,Stefanopoulos, Dimitria,Howard, Randy B.,Sundell, Cynthia L.,Saxena, Uday,Wasserman, Martin A.,Sikorski, James A.
, p. 6420 - 6432 (2007/10/03)
Vascular cell adhesion molecule-1 (VCAM-1) mediates recruitment of leukocytes to endothelial cells and is implicated in many inflammatory conditions. Since part of the signal transduction pathway that regulates the activation of VCAM-1 expression is redox