1427435-77-5

Basic information

• Product Name: 2-bromo-4,5-dimethoxy-N-((1R,5S)-2-methylene-5-(prop-1-en-2-yl)cyclohexyl)benzene sulfonamide
• Synonyms: 2-bromo-4,5-dimethoxy-N-((1R,5S)-2-methylene-5-(prop-1-en-2-yl)cyclohexyl)benzene sulfonamide
• CAS NO: 1427435-77-5
• Molecular Weight: 430.363
• Mol File: 1427435-77-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-bromo-4,5-dimethoxy-N-((1R,5S)-2-methylene-5-(prop-1-en-2-yl)cyclohexyl)benzene sulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-4,5-dimethoxy-N-((1R,5S)-2-methylene-5-(prop-1-en-2-yl)cyclohexyl)benzene sulfonamide(1427435-77-5)
• EPA Substance Registry System: 2-bromo-4,5-dimethoxy-N-((1R,5S)-2-methylene-5-(prop-1-en-2-yl)cyclohexyl)benzene sulfonamide(1427435-77-5)

Safety Data

• Hazardous Substances Data: 1427435-77-5(Hazardous Substances Data)

Upstream product

• 51072-64-1 2-bromo-4,5-dimethoxybenzene-1-sulfonyl chloride 

Downstream Products

• 1427435-79-7 (6S,7aR)-1-(2-bromo-4,5-dimethoxyphenylsulfonyl)-6-(prop-1-en-2-yl)-2,4,5,6,7,7a-hexahydro-1H-indole 
• 1427435-84-4 3a-(3,4-dimethoxyphenyl)-octahydroindol-6-ol 
• 1427435-85-5 3a-(4-methoxyphenyl)-octahydroindol-6-ol 
• 1427435-86-6 (3aR,6S,7aR)-benzyl 6-hydroxy-3a-(4-methoxyphenyl)octahydro-1Hindole-1-carboxylate 
• 1427435-87-7 (3aR,6S,7aR)-benzyl 3a-(3,4-dimethoxyphenyl)-6-hydroxyoctahydro-1H-indole-1-carboxylate 
• 1427472-33-0 (3aR,6S,7aR)-3a-(3,4-dimethoxyphenyl)-1-methyloctahydro-1H-indol-6-ol 
• 468-53-1 (3aR,7aR)-3a-(3,4-Dimethoxyphenyl)-1-methylhexahydro-1H-indol-6(2H)-one 
• 1427435-78-6 N-allyl-2-bromo-4,5-dimethoxy-N-((1R,5S)-2-methylene-5-(prop-1-en-2-yl)cyclohexyl)benzene sulfonamide 

Relevant articles and documents

Double reduction of cyclic aromatic sulfonamides: Synthesis of (+)-mesembrine and (+)-mesembranol

The synthesis of (+)-mesembrine (1) and (+)-mesembranol (2) has been achieved from the monoterpene (S)-(-)-perillyl alcohol. Key transformations include a diastereo- and regioselective Pd-mediated intramolecular Heck reaction, and a double reduction of the resultant cyclic sulfonamide, to afford the cis-3a-aryloctahydroindole skeleton.