1427472-33-0

Basic information

• Product Name: (3aR,6S,7aR)-3a-(3,4-dimethoxyphenyl)-1-methyloctahydro-1H-indol-6-ol
• Synonyms: (3aR,6S,7aR)-3a-(3,4-dimethoxyphenyl)-1-methyloctahydro-1H-indol-6-ol
• CAS NO: 1427472-33-0
• Molecular Weight: 291.39
• Mol File: 1427472-33-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3aR,6S,7aR)-3a-(3,4-dimethoxyphenyl)-1-methyloctahydro-1H-indol-6-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (3aR,6S,7aR)-3a-(3,4-dimethoxyphenyl)-1-methyloctahydro-1H-indol-6-ol(1427472-33-0)
• EPA Substance Registry System: (3aR,6S,7aR)-3a-(3,4-dimethoxyphenyl)-1-methyloctahydro-1H-indol-6-ol(1427472-33-0)

Safety Data

• Hazardous Substances Data: 1427472-33-0(Hazardous Substances Data)

Usage

Description

(3aR,6S,7aR)-3a-(3,4-dimethoxyphenyl)-1-methyloctahydro-1H-indol-6-ol is a synthetic compound with a complex molecular structure, classified as a derivative of octahydroindole. It features a substituted phenyl group with two methoxy substituents and is a stereochemical mixture, with the (3aR,6S,7aR) enantiomer being the most stable configuration. This chemical may possess potential pharmacological and biological activities, making it a candidate for further research and development in the pharmaceutical and chemical industries.

Uses

Used in Pharmaceutical Industry:
(3aR,6S,7aR)-3a-(3,4-dimethoxyphenyl)-1-methyloctahydro-1H-indol-6-ol is used as a potential pharmaceutical candidate for its possible pharmacological and biological activities. (3aR,6S,7aR)-3a-(3,4-dimethoxyphenyl)-1-methyloctahydro-1H-indol-6-ol's unique structure and stereochemistry may contribute to its potential therapeutic applications, warranting further investigation and development.
Used in Chemical Industry:
In the chemical industry, (3aR,6S,7aR)-3a-(3,4-dimethoxyphenyl)-1-methyloctahydro-1H-indol-6-ol may be utilized for the synthesis of other complex organic compounds or as an intermediate in the production of specialty chemicals. Its specific properties and reactivity could be harnessed for the creation of novel materials or chemical processes.

Upstream product

• 1427435-87-7 (3aR,6S,7aR)-benzyl 3a-(3,4-dimethoxyphenyl)-6-hydroxyoctahydro-1H-indole-1-carboxylate 
• 1427435-83-3 (2S,4aR,10aR)-2-acetoxy-6,7-dimethoxy-4a,10-ethano-2,3,4,4a,10,10a-hexahydro-1H-9-thia-10-aza-phenanthrene-9,9-dioxide 
• 1427435-82-2 (2S,4aR,10aR)-2-acetyl-6,7-dimethoxy-4a,10-ethano-2,3,4,4a,10,10a-hexahydro-1H-9-thia-10-aza-phenanthrene-9,9-dioxide 
• 1427435-81-1 (2S,4aR,10aR)-2-acetyl-6,7-dimethoxy-4a,10-etheno-2,3,4,4a,10,10a-hexahydro-1H-9-thia-10-aza-phenanthrene-9,9-dioxide 
• 1427435-80-0 (2S,4aR,10aR)-6,7-dimethoxy-4a,10-etheno-2,3,4,4a,10,10ahexahydro-1H-2-isopropenyl-9-thia-10-aza-phenanthrene 9,9-dioxide 
• 1427435-79-7 (6S,7aR)-1-(2-bromo-4,5-dimethoxyphenylsulfonyl)-6-(prop-1-en-2-yl)-2,4,5,6,7,7a-hexahydro-1H-indole 
• 1427435-78-6 N-allyl-2-bromo-4,5-dimethoxy-N-((1R,5S)-2-methylene-5-(prop-1-en-2-yl)cyclohexyl)benzene sulfonamide 
• 1427435-77-5 2-bromo-4,5-dimethoxy-N-((1R,5S)-2-methylene-5-(prop-1-en-2-yl)cyclohexyl)benzene sulfonamide 

Downstream Products

• 468-53-1 (3aR,7aR)-3a-(3,4-Dimethoxyphenyl)-1-methylhexahydro-1H-indol-6(2H)-one 

Relevant articles and documents

Double reduction of cyclic aromatic sulfonamides: Synthesis of (+)-mesembrine and (+)-mesembranol

The synthesis of (+)-mesembrine (1) and (+)-mesembranol (2) has been achieved from the monoterpene (S)-(-)-perillyl alcohol. Key transformations include a diastereo- and regioselective Pd-mediated intramolecular Heck reaction, and a double reduction of the resultant cyclic sulfonamide, to afford the cis-3a-aryloctahydroindole skeleton.