1429-05-6

Basic information

• Product Name: P-NITROBENZOIC ACID PHENYL ESTER
• Synonyms: 4-NITRO-BENZOIC ACID PHENYL ESTER;PHENYL 4-NITROBENZOATE;PHENYL-P-NITROBENZOATE;P-NITROBENZOIC ACID PHENYL ESTER
• CAS NO: 1429-05-6
• Molecular Formula: C₁₃H₉NO₄
• Molecular Weight: 243.21
• Product Categories: Aromatic Esters
• Mol File: 1429-05-6.mol
• Article Data: 61

Chemical Properties

• Boiling Point: 413.9°C at 760 mmHg
• Flash Point: 192.6°C
• Appearance: /
• Density: 1.316g/cm³
• Vapor Pressure: 4.65E-07mmHg at 25°C
• Refractive Index: 1.614
• CAS DataBase Reference: P-NITROBENZOIC ACID PHENYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: P-NITROBENZOIC ACID PHENYL ESTER(1429-05-6)
• EPA Substance Registry System: P-NITROBENZOIC ACID PHENYL ESTER(1429-05-6)

Safety Data

• Hazardous Substances Data: 1429-05-6(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 85, p. 2446, 1963 DOI: 10.1021/ja00899a024

InChI:InChI=1/C13H9NO4/c15-13(18-12-4-2-1-3-5-12)10-6-8-11(9-7-10)14(16)17/h1-9H

Upstream product

• 122-04-3 4-nitro-benzoyl chloride 
• 108-95-2 phenol 
• 62-23-7 4-nitro-benzoic acid 
• 17954-26-6 1,2-dihydro-2-phenoxycarbonylisoquinoline-1-carbonitrile 
• 139-02-6 sodium phenoxide 
• 100-66-3 methoxybenzene 
• 3847-57-2 sodium 4-nitrobenzoate 
• 1037-31-6 4-nitrophenyl 4-nitrobenzoate 
• 3229-70-7 phenolate 
• 102-09-0 bis(phenyl) carbonate 
• 7553-56-2 iodine 
• 71-43-2 benzene 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 13360-92-4 phenyl diphenylphosphinite 

Downstream Products

• 15850-20-1 4-nitro-N-(1,3-thiazol-2-yl)benzamide 
• 18920-70-2 4-hydroxy-4'-nitrobenzophenone 
• 68223-20-1 (2-hydroxyphenyl)(4-nitrophenyl)methanone 
• 36718-65-7 4-bromophenyl 4-nitrobenzoate 
• 10268-70-9 phenyl p-aminobenzoate 
• 34166-44-4 4,4'-azoxy-di-benzoic acid diphenyl ester 
• 33490-01-6 4-nitro-N-(2-nitrophenyl)benzamide 
• 3460-11-5 4-nitrobenzanilide 
• 139-29-7 N-(3-nitrophenyl)-4-nitro-benzamide 
• 64026-23-9 N-dodecyl-p-nitrobenzamide 
• 108-95-2 phenol 
• 93131-10-3 phenyl p-aminobenzoate hydrochloride 
• 62-23-7 4-nitro-benzoic acid 
• 55849-34-8 2-(p-Nitrobenzoyl)-1-indanon 

Relevant articles and documents

Palladium/NHC-catalyzed tandem benzylic oxidation/oxidative esterification of benzylic alcohols with phenols

A palladium/NHC-catalyzed tandem benzylic oxidation/oxidative esterification of benzylic alcohols with phenols to access aryl benzoate derivatives is described. The procedure tolerates a series of functional groups, such as methoxy, nitro, cyano, chloro, fluoro and bromo groups. Thus, it represents a practically alternative method to access aryl benzoate derivatives.

Mechanically induced solvent-free esterification method at room temperature

Herein, we describe two novel strategies for the synthesis of esters, as achieved under high-speed ball-milling (HSBM) conditions at room temperature. In the presence of I2 and KH2PO2, the reactions afford the desired esterification derivatives in 45% to 91% yields within 20 min of grinding. Meanwhile, using KI and P(OEt)3, esterification products can be obtained in 24% to 85% yields after 60 min of grinding. In addition, the I2/KH2PO2 protocol was successfully extended to the late-stage diversification of natural products showing the robustness of this useful approach. Further application of this method in the synthesis of inositol nicotinate was also discussed. This journal is

Design and Bioevaluation of Novel Hydrazide-Hydrazones Derived from 4-Acetyl-N-Substituted Benzenesulfonamide

Abstract: In this research, a series of hydrazine-hydrazone derivatives (Ia–g), (IIa–h) were synthesized to discover new antioxidant and anticholinesterase agents. The structures of synthesized compounds were characterized by spectroscopic data using UV, IR, 1H, 13C NMR, mass spectroscopy, and elemental analysis. The bio-evaluation of the synthesized compounds (Ia–g), (IIa–h) were evaluated according to in vitro activity assays. The results of β-carotene/linoleic acid assay showed that among the synthesized compounds, the (Ib), (Ie), (IIb–IIe), and (IIh) compound exhibited higher activity for the lipid peroxidation inhibitory activity. In the DPPH free scavenging activity and the cation radical scavenging activity in ABTS?+ activity, compound (IIb) was found to be more active. In the CUPRAC reduced power assay, the A0.5 values of all synthesized compounds were better than α-TOC. In AChE assay, compound (IIb) exhibited the most activity with IC50 = 11.12 ± 0.74 μM, while the compounds (Ib–g) and (IIb–h), exhibited excellent activity than the positive standard galantamine (IC50 = 46.06 ± 0.10 μM) in the BChE assay.