1429926-47-5Relevant articles and documents
Synthesis of 2-(3'-Indolyl)tetrahydrofurans by oxidative cycloetherification
Gillard, Rachel M.,Sperry, Jonathan
, p. 2900 - 2906 (2015)
A series of 2-(3'-indolyl)tetrahydrofurans have been prepared by a DDQ-mediated oxidative cycloetherification process. Performing the reaction under biphasic conditions prevents reductive cleavage of the products by the spent oxidant (DDQH2).
A combined theoretical and experimental investigation into the highly stereoselective migration of spiroindolenines
Zheng, Chao,Wu, Qing-Feng,You, Shu-Li
supporting information, p. 4357 - 4365 (2013/06/26)
This paper describes a combined theoretical and experimental investigation into the acid-catalyzed migration of spiroindolenines to the corresponding fused cyclic products. It is suggested that the three-center-two- electron -type transition state is the crucial reason accounting for the highly stereoselective phenomenon. Further studies demonstrated that the electronic property of the migratory group as well as the ring size may have a major influence on the reaction profile of the migration process. Some predictions based on the computational results were supported by additional experiments.