1430074-80-8Relevant articles and documents
Metal-free synthesis of imidazo[1,5- a] pyridines via elemental sulfur mediated sequential dual oxidative Csp3-H amination
Sheng, Jie,Liu, Jidan,Zhao, He,Zheng, Liyao,Wei, Xingchuan
supporting information, p. 5570 - 5574 (2018/08/17)
A simple and efficient approach has been developed for the synthesis of imidazo[1,5-a]pyridines using the elemental sulfur mediated sequential dual oxidative Csp3-H amination of 2-pyridyl acetates and amines under metal- and peroxide-free conditions. Broad substrate scope, operational simplicity and gram-scale ability make this chemistry very practical.
Mild metal-free sequential dual oxidative amination of C(sp3)-H bonds: Efficient synthesis of imidazo[1,5-a]pyridines
Yan, Yizhe,Zhang, Yonghui,Zha, Zhenggen,Wang, Zhiyong
supporting information, p. 2274 - 2277 (2013/06/05)
A metal-free sequential dual oxidative amination of C(sp3)-H bonds under ambient conditions was the first developed, affording imidazo[1,5-a]pyridines in good to excellent yields. The reaction was involved in two oxidative C-N couplings and one oxidative dehydrogenation process with six hydrogen atoms removed.