1451194-92-5Relevant articles and documents
Design, synthesis and biological evaluation of imidazo[1,5-a]pyridine-PBD conjugates as potential DNA-directed alkylating agents
Kamal, Ahmed,Ramakrishna,Ramaiah, M. Janaki,Viswanath,Rao, A. V. Subba,Bagul, Chandrakant,Mukhopadyay, Debasmitha,Pushpavalli,Pal-Bhadra, Manika
, p. 697 - 703 (2013/06/05)
A series of novel imidazo[1,5-a]pyridine-PBD conjugates were synthesized and evaluated for their antitumor activity in breast cancer cell line (MCF-7). Interestingly, all the compounds showed enhanced DNA binding ability. These conjugates showed significa