1431329-92-8

Basic information

• Product Name: C₄₃H₅₈N₂O₅
• Synonyms: C₄₃H₅₈N₂O₅
• CAS NO: 1431329-92-8
• Molecular Weight: 682.944
• Mol File: 1431329-92-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₄₃H₅₈N₂O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₃H₅₈N₂O₅(1431329-92-8)
• EPA Substance Registry System: C₄₃H₅₈N₂O₅(1431329-92-8)

Safety Data

• Hazardous Substances Data: 1431329-92-8(Hazardous Substances Data)

Upstream product

• 1322548-02-6 C₁₈H₂₈N₂O₃ 
• 1322546-79-1 tert-butyl(dimethyl){[1-(phenylsulfonyl)cyclopent-3-en-1-yl]methoxy}silane 
• 140840-85-3 3-(((tert-butyldimethylsilyl)oxy)methyl)cyclopent-2-en-1-one 
• 1322547-96-5 [(1S,3S)-3-{1-[(4-methylphenyl)sulfonyl]-1H-pyrrol-2-yl}cyclopentyl]methanol 
• 1322546-82-6 C₁₈H₂₈O₄SSi 
• 1322546-81-5 C₁₈H₃₀O₄SSi 
• 1322546-76-8 C₁₂H₁₄O₃S 
• 777-93-5 5-(p-tolyl)pentanoic acid 
• 5724-05-0 5-(p-tolyl)pent-4-enoic acid 
• 17857-14-6 (3-carboxypropyl)(triphenyl)phosphonium bromide 
• 1322548-01-5 tert-Butyl(5R,7S)-2,2-dimethyl-7-{1-[(4-methylphenyl)sulfonyl]-1H-pyrrol-2-yl}-3-oxa-1-azaspiro [4.4]nonane-1-carboxylate 
• 1322548-00-4 tert-Butyl [(1R,3S)-1-(hydroxymethyl)-3-{1-[(4-methylphenyl)sulfonyl]-1H-pyrrol-2-yl}cyclopentyl] carbamate 
• 1322547-99-8 tert-butyl (5R,7S)-7-{1-[(4-methylphenyl)sulfonyl]-1H-pyrrol-2-yl}-2-oxo-3-oxa-1-azaspiro[4.4] nonane-1-carboxylate 
• 1322547-98-7 (5R,7S)-7-{1-[(4-methylphenyl)sulfonyl]-1H-pyrrol-2-yl}-3-oxa-1-azaspiro[4.4]nonan-2-one 

Downstream Products

• 1431329-93-9 tert-butyl (5R,7S)-2,2-dimethyl-7-{1-methyl-5-[5-(4-methylphenyl)pentanoyl]-1H-pyrrol-2-yl}-3-oxa-1-azaspiro[4.4]nonane-1-carboxylate 
• 1322547-44-3 1-{5-[(1S,3R)-3-amino-3-(hydroxymethyl)cyclopentyl]-1-methyl-1H-pyrrol-2-yl}-5-(4-methylphenyl)pentan-1-one 

Relevant articles and documents

Synthesis of (3S)-(tert-butyldimethylsilyloxy)methylcyclopentan-1-one as a key intermediate of sphingosine 1-phosphate-1 receptor agonists

Herein we report the asymmetric synthesis of (3S)-(tert- butyldimethylsilyloxy)methylcyclopentan-1-one (S)-3 as a practical chiral synthon for a wide range of pharmaceutical and/or natural products, using Lipshutz's asymmetric copper-catalyzed conjugate reduction. This method makes it feasible to prepare a conformationally constrained cyclopentane analogue 12, which is one of the key intermediates for the synthesis of novel sphingosine 1-phosphate-1 receptor agonists.