143141-23-5

Basic information

• Product Name: 1H-Pyrrolo[2,3-b]pyridine, 1-(phenylsulfonyl)-
• Synonyms: 1H-Pyrrolo[2,3-b]pyridine, 1-(phenylsulfonyl)-;1-(Phenylsulfonyl)-7-azaindole;1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine;1-(Benzenesulfonyl)pyrrolo[2,3-b]pyridine;1-(Phenylsulphonyl)-7-azaindole;N-Benzenesulfonyl-7-azaindole
• CAS NO: 143141-23-5
• Molecular Formula: C₁₃H₁₀N₂O₂S
• Molecular Weight: 258.3
• Product Categories: Heterocycle-Pyridine series
• Mol File: 143141-23-5.mol
• Article Data: 26

Chemical Properties

• Boiling Point: 465.8 °C at 760 mmHg
• Flash Point: 235.5 °C
• Appearance: /
• Density: 1.34 g/cm³
• CAS DataBase Reference: 1H-Pyrrolo[2,3-b]pyridine, 1-(phenylsulfonyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[2,3-b]pyridine, 1-(phenylsulfonyl)-(143141-23-5)
• EPA Substance Registry System: 1H-Pyrrolo[2,3-b]pyridine, 1-(phenylsulfonyl)-(143141-23-5)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 143141-23-5(Hazardous Substances Data)

Usage

General Description

1H-Pyrrolo[2,3-b]pyridine, 1-(phenylsulfonyl)- is a chemical compound that belongs to the class of pyrrolopyridine derivatives. It is known for its potential application as an inhibitor in pharmaceutical research. The phenylsulfonyl group attached to the pyrrolopyridine ring plays a crucial role in modulating the biological activity of the compound. This chemical has shown promise in medicinal chemistry due to its ability to target specific enzymes and receptors, making it a valuable candidate for drug development. Furthermore, the unique structure of 1H-Pyrrolo[2,3-b]pyridine, 1-(phenylsulfonyl)- makes it a key molecule for further studies and exploration in the field of organic synthesis and drug discovery.

Upstream product

• 271-63-6 7-Azaindole 
• 98-09-9 benzenesulfonyl chloride 

Downstream Products

• 861045-11-6 2-benzenesulfonylamino-nicotinic acid 
• 189089-88-1 (1-Benzenesulfonyl-1H-pyrrolo[2,3-b]pyridin-2-yl)-thiophen-2-yl-methanol 
• 189089-91-6 1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carbaldehyde 
• 189089-90-5 1-(phenyl-sulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid 
• 189089-86-9 (1-Benzenesulfonyl-1H-pyrrolo[2,3-b]pyridin-2-yl)-(4-chloro-phenyl)-methanol 
• 189089-83-6 1-benzenesulfonyl-2-methyl-1H-pyrrolo[2,3-b]pyridine 
• 282734-63-8 2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine 
• 265647-76-5 1-(benzenesulfonyl)-2-(2-pyridyl)-7-azaindole 
• 880769-95-9 3-bromo-1-(benzenesulfonyl)-1H-pyrrolo [2,3-b]pyridine 
• 886547-96-2 3-(2-chloropyrimidin-4-yl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine 
• 886546-35-6 cyclohexyl-[4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-yl]amine 

Relevant articles and documents

ESTROGEN RECEPTOR ANTAGONIST

Provided is an indole compound. In particular, disclosed are a compound represented by formula (II) or an isomer or pharmaceutically acceptable salt thereof and a use of the same as an estrogen receptor antagonist in preparing a drug for treating estrogen receptor-positive breast cancer.

Design and synthesis of azaindole heterocycle decorated new scaffold in fluorometric sensing of F? and H2PO4?

7-Azaindole has been used in designing new molecular structure 1 on enediyne spacer for its application in anion sensing. New structure 1 has been established as efficient fluorescent sensor of H2PO4? and F? ion

Synthesis, biological evaluation and molecular modeling of a novel series of 7-azaindole based tri-heterocyclic compounds as potent CDK2/Cyclin E inhibitors

From four molecules, inspired by the structural features of fascaplysin, with an interesting potential to inhibit cyclin-dependent kinases (CDKs), we designed a new series of tri-heterocyclic derivatives based on 1H-pyrrolo[2,3-b]pyridine (7-azaindole) an