886546-35-6Relevant articles and documents
Synthesis of 2-amino-4-(7-azaindol-3-yl)pyrimidines as cyclin dependent kinase 1 (CDK1) inhibitors
Huang, Shenlin,Li, Ronghua,Connolly, Peter J.,Emanuel, Stuart,Middleton, Steven A.
, p. 4818 - 4821 (2007/10/03)
A novel series of 2-amino-4-(7-azaindol-3-yl)pyrimidines was discovered as cyclin dependent kinase 1 (CDK1) inhibitors. The core structure was synthesized via Pd(II) catalyzed coupling reaction. A number of analogues showed good potency for CDK1 and exhib