143224-83-3Relevant articles and documents
Nonpeptidic lysosomal modulators derived from Z-Phe-Ala-diazomethylketone for treating protein accumulation diseases
Viswanathan, Kishore,Hoover, Dennis J.,Hwang, Jeannie,Wisniewski, Meagan L.,Ikonne, Uzoma S.,Bahr, Ben A.,Wright, Dennis L.
, p. 920 - 924 (2013/01/15)
Lysosomes are involved in protein turnover and removing misfolded species, and their enzymes have the potential to offset the defect in proteolytic clearance that contributes to the age-related dementia Alzheimer's disease (AD). The weak cathepsin B and L
COMPOUNDS FOR LYSOSOMAL MODULATION AND METHODS OF USE
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, (2009/12/02)
Compounds useful for promoting lysosomal processes and thereby ameliorating the disruption of cellular and functional integrity induced by Aβ and other protein and glycoconjugate species are provided. Methods for the treatment of neurodegenerative disease
Inhibitors of HIV-1 Protease Containing the Novel and Potent (R)-(Hydroxyethyl)sulfonamide Isostere
Vazquez, Michael L.,Bryant, Martin L.,Clare, Michael,DeCrescenzo, Gary A.,Doherty, Elizabeth M.,et al.
, p. 581 - 584 (2007/10/02)
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