116949-67-8

Basic information

• Product Name: (2S,3S)-2-azido-1-phenyl-butane-3,4-diol
• Synonyms: (2S,3S)-2-azido-1-phenyl-butane-3,4-diol
• CAS NO: 116949-67-8
• Molecular Weight: 207.232
• Mol File: 116949-67-8.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: (2S,3S)-2-azido-1-phenyl-butane-3,4-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-2-azido-1-phenyl-butane-3,4-diol(116949-67-8)
• EPA Substance Registry System: (2S,3S)-2-azido-1-phenyl-butane-3,4-diol(116949-67-8)

Safety Data

• Hazardous Substances Data: 116949-67-8(Hazardous Substances Data)

Upstream product

• 140867-27-2 (2R,3R)-1,2-O-methylethylidene-4-phenylbutane-1,2,3-triol 
• 122-78-1 phenylacetaldehyde 
• 591-51-5 phenyllithium 
• 54966-42-6 ethyl 3-benzylacrylate 
• 42238-15-3 (2E)-4-phenylbut-2-en-1-ol 
• 161170-92-9 (2S,3R)-2-Hydroxymethyl-3-phenylmethyloxirane 
• 147915-01-3 (2S,3S)-3-azido-1,2-O-methylethylidene-4-phenylbutane-1,2-diol 
• 78571-81-0 (R,R)-3-(phenylmethyl)oxiranemethanol 

Downstream Products

• 147976-16-7 (4S,5S)-5-hydroxymethyl-4-phenylmethyloxazolidinone 
• 147976-18-9 (4S,5S)-4-benzyl-2-oxo-oxazolidine-5-carboxylic acid 
• 162221-36-5 (4S,5S)-4-benzyl-2-oxo-oxazolidine-5-carboxylic acid methyl ether 
• 136465-97-9 4(S)-(1(S)-Azido-2-phenylethyl)-1,3,2-dioxathiolane 2,2-dioxide 
• 1190630-69-3 (2R,3S)-3-Cbz-amino-2-hydroxy-4-phenyl-1-(N-benzylacetamido)butane 
• 1190630-70-6 (2R,3S)-3-Cbz-amino-2-hydroxy-4-phenyl-1-(N-benzyl-2-diazo-ethanamido)butane 
• 1400634-51-6 C₃₄H₄₀N₂O₆ 
• 1190630-76-2 [(1S,2R)-1-benzyl-3-benzylamino-2-(tetrahydropyran-2-yloxy)propyl]carbamic acid benzyl ester 
• 1190630-74-0 [(2R,3S)-3-azido-4-phenyl-2-(tetrahydropyran-2-yloxy)butyl]benzylamine 
• 1190630-73-9 toluene-4-sulfonic acid 3-azido-4-phenyl-2-(tetrahydropyran-2-yloxy)butyl ester 
• 143224-83-3 (2R,3S)-3-Cbz-amino-2-hydroxy-4-phenyl-1-benzylaminobutane 
• 1190630-75-1 (2R,3S)-3-amino-2-tetrahydropyranyloxy-4-phenyl-1-benzylaminobutane 
• 17585-69-2 L-phenylalanine hydrochloride 
• 150331-86-5 N-tert-butyl-2-(2(R)-hydroxy-4-phenyl-3(S)-((2(S)-azido-2(3(R)-tetrahydrothiofuranyl)acetyl)amino)butyl)decahydro-(4aS,8aS)-isoquinoline-3(S)-carboxamide 

Relevant articles and documents

A simple and inexpensive procedure for low valent copper mediated benzylation of aldehydes in wet medium

An operationally simple, inexpensive and efficient procedure for benzylation of aldehydes in wet medium has been developed that was mediated with low valent copper, prepared in situ through spontaneous reduction of CuCl 2-2H2O with magnesium in situ. Notably, copper mediated benzylation of 3h took place with good syn selectivity that was opposite to that for the corresponding Grignard addition. Finally, homobenzyl alcohol 5a was elegantly transformed into a known protease inhibitor synthon I. ARKAT USA, Inc.

Enantiodivergent, catalytic asymmetric synthesis of γ-amino vinyl sulfones

A set of diversely substituted N-Boc-γ-amino vinyl sulfones has been prepared by a four-step procedure from readily available, highly enantiopure anti-N-Boc-3-amino-1,2-alkanediols. This new route, which does not depend on the accessibility of α-amino acids as starting materials, is noteworthy for its efficiency, for its generality, and for the fact that both enantiomers of a given γ-amino vinyl sulfone can be obtained with equal ease.

Synthesis of conformationally restricted mimetics of γ-turns and incorporation into desmopressin, an analogue of the peptide hormone vasopressin

Mimetics of tripeptides adopting inverse and classical γ-turn conformations have been designed and synthesized by an enantioselective approach and then incorporated in an analogue of the hormone vasopressin. In the mimetics one of the amide bonds of the γ