143360-89-8

Basic information

• Product Name: Acetamide, 2,2,2-trifluoro-N-[2-(phenylethynyl)phenyl]-
• CAS NO: 143360-89-8
• Molecular Formula: C16H10F3NO
• Molecular Weight: 289.257
• Mol File: 143360-89-8.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: Acetamide, 2,2,2-trifluoro-N-[2-(phenylethynyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, 2,2,2-trifluoro-N-[2-(phenylethynyl)phenyl]-(143360-89-8)
• EPA Substance Registry System: Acetamide, 2,2,2-trifluoro-N-[2-(phenylethynyl)phenyl]-(143360-89-8)

Safety Data

• Hazardous Substances Data: 143360-89-8(Hazardous Substances Data)

Usage

General Description

Acetamide, 2,2,2-trifluoro-N-[2-(phenylethynyl)phenyl]- is a chemical compound that is characterized by its trifluoromethyl and phenylethynyl substituents. It is commonly used in the field of organic synthesis and pharmaceutical research due to its unique structure and properties. Acetamide, 2,2,2-trifluoro-N-[2-(phenylethynyl)phenyl]- is known to exhibit potent inhibitory effects on various enzyme systems, making it a valuable tool in biochemical studies. Additionally, it has been investigated for its potential therapeutic applications in the treatment of various diseases and disorders. Overall, acetamide, 2,2,2-trifluoro-N-[2-(phenylethynyl)phenyl]- is a versatile compound with promising applications in both research and medicine.

Upstream product

• 143321-89-5 2,2,2-trifluoro-N-(2-iodophenyl)acetamide 
• 536-74-3 phenylacetylene 
• 354-32-5 trifluoracetyl chloride 
• 13141-38-3 2-phenylethynylaniline 
• 615-43-0 2-iodophenylamine 
• 103529-16-4 2-[(trimethylsilyl)ethynyl]aniline 
• 52670-38-9 2-ethynylaniline 
• 591-50-4 iodobenzene 
• 1006727-95-2 allyl(2-ethynylphenyl)amine 
• 143360-93-4 N-(2-ethynylphenyl)-2,2,2-trifluoroacetamide 
• 62926-91-4 N-(2-chlorophenyl)-2,2,2-trifluoro-acetamide 
• 358-23-6 trifluoromethylsulfonic anhydride 
• 68-12-2 N,N-dimethyl-formamide 
• 615-36-1 2-bromoaniline 

Downstream Products

• 143360-82-1 3-(4-chlorophenyl)-2-phenyl-1H-indole 
• 143360-83-2 3-((E)-Cyclooct-1-enyl)-2-phenyl-1H-indole 
• 103056-99-1 (4-methoxyphenyl)(2-phenyl-1H-indol-3-yl)methanone 
• 201813-54-9 N-Allyl-2,2,2-trifluoro-N-(2-phenylethynyl-phenyl)-acetamide 
• 201813-59-4 2,2,2-Trifluoro-N-(2-methyl-allyl)-N-(2-phenylethynyl-phenyl)-acetamide 
• 948-65-2 2-phenyl-indole 
• 581783-28-0 2-phenyl-3-thiazol-2-yl-1H-indole 
• 91025-04-6 2-phenyl-3-(2-pyridyl)indole 
• 3469-20-3 2,3-diphenyl-1H-indole 
• 2415-33-0 2,2'-diphenyl-1H,1'H-3,3'-biindole 

Relevant articles and documents

Synthesis of readily cleavable immobilized 1,10-phenanthroline resins

(Equation Presented) 1,10-Phenanthroline is derivatized and ultimately immobilized on two different polystyrene/divinylbenzene solid supports using convenient methodology. All syntheses are amenable to semiautomatic processing and are scalable for high-throughput screening. A domino copper-catalyzed coupling-cyclization reaction is used to illustrate applicability in catalytic studies.

Palladium-catalyzed: C -glycosylation and annulation of o -alkynylanilines with 1-iodoglycals: Convenient access to 3-indolyl- C -glycosides

An efficient and practical approach for the synthesis of 3-indolyl-C-Δ1,2-glycosides through a palladium-catalyzed annulation/C-glycosylation sequence of o-alkynylanilines with 1-iodoglycals has been developed. This methodology has a wide scope of substra

A Commercially Available and User-Friendly Catalyst for Hydroamination Reactions under Technical Conditions

The activity of a simple, commercially available copper salt, [Cu(NCMe)4](BF4) in intramolecular hydroamination reactions of alkynes and allenes is presented. Reactions were successfully carried out in technical acetonitrile in the presence of air. While attempts of alkene hydroamination failed, this catalyst was also found active in intermolecular aza-Michael reactions.