143468-08-0

Basic information

• Product Name: 1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile, 1-benzoyl-
• CAS NO: 143468-08-0
• Molecular Formula: C15H9N3O
• Molecular Weight: 247.256
• Mol File: 143468-08-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile, 1-benzoyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile, 1-benzoyl-(143468-08-0)
• EPA Substance Registry System: 1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile, 1-benzoyl-(143468-08-0)

Safety Data

• Hazardous Substances Data: 143468-08-0(Hazardous Substances Data)

Upstream product

• 143468-12-6 1-Benzoyl-6-bromo-1H-pyrrolo<2,3-b>pyridine 
• 7677-24-9 trimethylsilyl cyanide 
• 98-88-4 benzoyl chloride 
• 55052-24-9 1H-Pyrrolo[2,3-b]pyridine-7-oxide 

Downstream Products

• 189882-33-5 1H-pyrrolo[2,3-b]pyridine-6-carbonitrile 

Relevant articles and documents

Preparation method of 6-cyano-7-azaindole and derivative thereof

The invention discloses a preparation method of 6-cyano-7-azaindole and a derivative thereof, which comprises the following steps: dissolving a compound represented by formula (1) in a solvent, and performing a reaction with an organic alkali and a cyaniding reagent under the action of a catalyst to obtain the final product represented by formula (2). According to the process disclosed by the invention, the safe and non-toxic potassium ferrocyanide is used as a cyano source, the reaction operation is simple and convenient, the yield is high, the influence on the environment is relatively small, and the process is suitable for preparing the 6-cyano-7-azaindole and the derivative 1-benzoyl-6-cyano-7-azaindole thereof on a large scale.