1436413-96-5Relevant articles and documents
Design, synthesis and antimicrobial activities evaluation of Schiff base derived from secnidazole derivatives as potential FabH inhibitors
Li, Yao,Zhao, Chang-Po,Ma, Hua-Ping,Zhao, Meng-Yue,Xue, Ya-Rong,Wang, Xiao-Ming,Zhu, Hai-Liang
, p. 3120 - 3126 (2013/07/05)
FabH, β-ketoacyl-acyl carrier protein (ACP) synthase III, is critically important to the initiation of fatty acid biosynthesis and is highly conserved among Gram-positive and Gram-negative bacteria. A series of novel secnidazole derivatives (1-20) were sy