5779-74-8

Basic information

• Product Name: Benzaldehyde, 3,4,5-trimethyl-
• CAS NO: 5779-74-8
• Molecular Formula: C10H12O
• Molecular Weight: 148.205
• Mol File: 5779-74-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 3,4,5-trimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 3,4,5-trimethyl-(5779-74-8)
• EPA Substance Registry System: Benzaldehyde, 3,4,5-trimethyl-(5779-74-8)

Safety Data

• Hazardous Substances Data: 5779-74-8(Hazardous Substances Data)

Upstream product

• 576-26-1 2.6-dimethylphenol 
• 13061-96-6 dihydroxy-methyl-borane 
• 188112-49-4 trifluoromethanesulfonic acid 4-formyl-2,6-dimethylphenyl ester 
• 2047-21-4 3,4,5-trimethylacetophenone 
• 1076-88-6 3,4,5-trimethylbenzoic acid 
• 527-53-7 1,2,3,5-Tetramethylbenzene 
• 57498-46-1 3,4,5-trimethyl-benzoyl chloride 
• 39126-11-9 3,4,5-trimethylbenzyl alcohol 

Downstream Products

• 1593978-40-5 (Z)-methyl α-acetamido-3-(3,4,5-trimethylphenyl)acrylate 
• 1531637-48-5 C₂₇H₂₅NO₂ 
• 1531637-46-3 C₂₂H₂₃NO₂ 
• 1436413-96-5 (E)-2-(2-methyl-5-nitro-1H-imidazol-1-yl)-N'-(3,4,5-trimethylbenzylidene)acetohydrazide 
• 103565-14-6 2-Nitro-3,4,5-trimethyl-phenyl-acetaldoxim 
• 100061-17-4 3,4,5-Trimethyl-2,β-dinitro-styrol 
• 99060-33-0 2-Nitro-3,4,5-trimethyl-benzaldehyd 
• 36321-76-3 2,6-Dinitro-3,4,5-trimethyl-benzaldehyd 
• 32156-17-5 1-methyl-2-(3,4,5-trimethyl-phenyl)-ethylamine 

Relevant articles and documents

A convenient synthesis of tri- and tetramethylbenzaldehydes from readily available phenols

This letter describes a convenient synthesis of the six isomeric tri- and tetramethylbenzaldehydes, which are not readily available from major chemical suppliers. Formylation of readily available phenols via electrophilic aromatic substitution provides compounds containing the correct aromatic substitution pattern. ?Suzuki cross-coupling of the corresponding trifluoromethanesulfonates with methylboronic acid then provides the benzaldehydes as single isomers. Georg Thieme Verlag Stuttgart. New York.

THE PHENYLCARBENE REARRANGEMENT REVISITED

The evolution of mechanistic ideas about the phenylcarbene rearrangement has been reviewed, and three closely linked problems have been identified toward whose solution this research has been aimed: 1.Why do the ratios of the stable end products from the rearrangements of o-, m- and p-tolylmethylene differ when all three reactions have been thought to pass through a common intermediate? 2.Why does the rearrangement of 2-methylcycloheptatrienylidene lead to exclusive formation of styrene? 3.What is the mechanism of styrene formation from o-tolylmethylene? New mechanisms have been proposed in which m- and p-tolylmethylene can rearrange to styrene without necessarily being converted to o-tolylmethylene.The formation of a small amount of 2,6-dimethylstyrene from the rearrangement of 3,4,5-trimethylphenylmethylene is viewed as evidence for such a mechanism, and a set of interconverting norcaradienylidenes are believed to be the crucial intermediates.Other alternatives are considered and rejected on the basis of the rearrangement products of 3,5-dimethyl- and 3,4,5-trimethylphenylmethylene.