14374-54-0

Basic information

• Product Name: 5-(4-methoxyphenyl)pentan-1-ol
• CAS NO: 14374-54-0
• Molecular Weight: 194.274
• Mol File: 14374-54-0.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 5-(4-methoxyphenyl)pentan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-methoxyphenyl)pentan-1-ol(14374-54-0)
• EPA Substance Registry System: 5-(4-methoxyphenyl)pentan-1-ol(14374-54-0)

Safety Data

• Hazardous Substances Data: 14374-54-0(Hazardous Substances Data)

Upstream product

• 79023-06-6 5-(4-methoxyphenyl)pentanoic acid ethyl ester 
• 71-36-3 butan-1-ol 
• 5390-04-5 pent-1-yn-5-ol 
• 696-62-8 para-iodoanisole 
• 15823-04-8 methyl 3-(4-methoxyphenyl)propionate 
• 1929-29-9 3-(4-methoxyphenyl)propanoic acid 
• 943-89-5 (E)-3-(4-methoxyphenyl)acrylic acid 
• 109-99-9 tetrahydrofuran 
• 38769-92-5 4-methoxybenzylmagnesium chloride 
• 22767-72-2 ethyl 3-(4-methoxyphenyl)propanoate 
• 344360-08-3 5-(4-methoxyphenyl)pent-2-enoic acid ethyl ester 
• 24393-56-4 ethyl p-methoxycinnamate 
• 20401-88-1 3-(4-methoxyphenyl)propional 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 104375-73-7 N-tosyl-2-(p-methoxyphenyl)piperidine 
• 905293-02-9 tert-butyl (5-(4-methoxyphenyl)pentyl)carbamate 
• 7508-04-5 5-(4-methoxyphenyl)pentanoic acid 

Relevant articles and documents

GLYCOSIDE COMPOUND AND PREPARATION METHOD THEREFOR, COMPOSITION, APPLICATION, AND INTERMEDIATE

The present invention discloses a glycoside compound represented by Formula III, and a preparation method, a composition, use and an intermediate thereof. The glycoside compound provided in the present invention has simple preparation method, can significantly increase the expression of VEGF-A mRNA, and is effective in promoting the angiogenesis. This provides a reliable guarantee for the development of drugs with pro-angiogenic activity for treating cerebral infarction cerebral stroke, myocardial infarction, and ischemic microcirculatory disturbance of lower limbs.

Synthesis, in vitro and in silico evaluation of diaryl heptanones as potential 5LOX enzyme inhibitors

A new series of diaryl heptanones (12a-q) were synthesized and their structures were confirmed by its 1H, 13C NMR and Mass spectral data. These analogs were evaluated for their anti-oxidant activity and potential to inhibit 5-lipoxygenase. Compounds 12k and 12o showed potent in vitro 5-lipoxygenase enzyme inhibitory activity with IC50 values of 22.2, 21.5 μM, which are comparable to curcumin (24.4 μM). Further they also have shown significant antioxidant activity. Molecular docking studies clearly showed correlation between binding energy and potency of these compounds.

Discovery of synthetic methoxy-substituted 4-phenylbutyric acid derivatives as chemical chaperones

In this study, we evaluated the chemical chaperone activity of synthetic 4-phenylbutyric acid (4-PBA) derivatives. These derivatives have a methoxy group at the benzene ring and/or longer or shorter fatty acid portions. Several 4-PBA derivatives demonstrated higher antiaggregation activity than 4-PBA. Moreover, 4-(4-methoxyphenyl)butanoic acid (7b) showed protective effects against endoplasmic reticulum stress-induced neuronal cell death.