143745-68-0

Basic information

• Product Name: 2-METHYL-1-O-TOLYLPROPAN-2-AMINE HCL
• Synonyms: 2-METHYL-1-O-TOLYLPROPAN-2-AMINE HCL
• CAS NO: 143745-68-0
• Molecular Weight: 163.263
• Mol File: 143745-68-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-METHYL-1-O-TOLYLPROPAN-2-AMINE HCL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-1-O-TOLYLPROPAN-2-AMINE HCL(143745-68-0)
• EPA Substance Registry System: 2-METHYL-1-O-TOLYLPROPAN-2-AMINE HCL(143745-68-0)

Safety Data

• Hazardous Substances Data: 143745-68-0(Hazardous Substances Data)

Upstream product

• 26654-39-7 4,4-dimethyl-1,3-oxazolidin-2-one 
• 137-06-4 2-thiocresol 
• 5916-21-2 o-methyl-β,β-dimethylstyrene 
• 552-45-4 1-chloromethyl-2-methylbenzene 

Downstream Products

• 693263-37-5 2-(1,1-dimethyl-2-o-tolyl-ethylamino)-1-(3,4-dibenzyloxy-2-methyl-phenyl)-ethanone hydrochloride 
• 912290-06-3 C₅H₄NCHNCH(CH₂C₆H₅)(COOCH₃) 
• 6389-56-6 2-phenyl-N-(pyridine-2-ylmethylene)ethanamine 
• 677777-28-5 2-(1,1-dimethyl-2-o-tolyl-ethylamino)-1-(4-methoxy-2,2-diphenyl-benzo[1,3]dioxol-5-yl)-ethanone hydrochloride 

Relevant articles and documents

ONE STEP PROCESS FOR THE PREPARATION OF PHENYL ETHYL AMINE DERIVATIVES

The present invention relates to a novel process for the preparation of phenyl ethyl amine derivatives by reacting a phenyl ethyl hydroxy compound with hydrogen cyanide followed by in situ hydrolysis.

Novel synthesis method of 2-methyl-1-substituted phenyl-2-propylamine compounds

The invention discloses a novel synthesis method of 2-methyl-1-substituted phenyl-2-propylamine compounds, and belongs to the field of material synthesis. The method comprises steps as follows: substituted benzyl halide is taken as a raw material and subj

Use of 5-hydroxy-4H-benzo[1,4]oxazin-3-ones as β2-adrenoceptor agonists

Novel β2-agonists with a 5-hydroxy-4H-benzo[1,4]oxazin-3-one moiety as head group are described. Systematic chemical variations at the phenethylamine residue of these compounds lead to the discovery of compound 6m as potent, full agonist of the β2-adrenoceptor with a high β1/β2-selectivity. Molecular modeling revealed an interaction between the carboxylic acid group of 6m and a lysine residue (K305) of the β2-receptor as putative explanation for the high observed selectivity. Further, compound 6m displayed in a guinea pig in vivo model a complete reversal of acetylcholine induced bronchoconstriction which lasted over the complete study time of 5 h.