143806-91-1

Basic information

• Product Name: 3-Pyridinecarbonitrile, 1-[[[dimethyl(1,1,2-trimethylpropyl)silyl]oxy]methyl]-1,4-dihydro-4-phenyl-
• CAS NO: 143806-91-1
• Molecular Formula: C21H30N2OSi
• Molecular Weight: 354.567
• Mol File: 143806-91-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Pyridinecarbonitrile, 1-[[[dimethyl(1,1,2-trimethylpropyl)silyl]oxy]methyl]-1,4-dihydro-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarbonitrile, 1-[[[dimethyl(1,1,2-trimethylpropyl)silyl]oxy]methyl]-1,4-dihydro-4-phenyl-(143806-91-1)
• EPA Substance Registry System: 3-Pyridinecarbonitrile, 1-[[[dimethyl(1,1,2-trimethylpropyl)silyl]oxy]methyl]-1,4-dihydro-4-phenyl-(143806-91-1)

Safety Data

• Hazardous Substances Data: 143806-91-1(Hazardous Substances Data)

Upstream product

• 16635-23-7 phenyltriisopropoxytitanium(IV) 
• 144028-48-8 3-cyano-1-(dimethylthexylsilyloxy)methylpyridinium chloride 
• 100-54-9 pyridine-3-carbonitrile 
• 125816-34-4 1-chloro-3,3,4,4,5-pentamethyl-2-oxa-3-silahexane 

Downstream Products

• 39065-51-5 4-phenylpyridine-3-carbonitrile 

Relevant articles and documents

Aryl- and Alkynyltri-isopropoxytitanium Reagents in Regioselective Carbon-Carbon Bond Formation in Azines

Regioselective arylation in the 4-position in pyridines results from 1:1-adduct formation between an aryltriisopropoxytitanium reagent and N-isobutyloxycarbonyl- or an N-silyloxymethyl-3-cyanopyridinium salt after successive DDQ dehydrogenation and cleavage of the 1-substituent.Complete regioselectivity for new C-C bond formation in the 4-position results in the adduct formation between aryl- and phenylethynyltri-isopropoxytitanium reagents and pyrimidin-2(1H)-ones; with ethynyltriisopropoxytitanium the new C-C bond formation occurs at the 6-position.