143879-15-6

Basic information

• Product Name: Pentanal, 2-(phenylthio)-
• CAS NO: 143879-15-6
• Molecular Formula: C11H14OS
• Molecular Weight: 194.298
• Mol File: 143879-15-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Pentanal, 2-(phenylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pentanal, 2-(phenylthio)-(143879-15-6)
• EPA Substance Registry System: Pentanal, 2-(phenylthio)-(143879-15-6)

Safety Data

• Hazardous Substances Data: 143879-15-6(Hazardous Substances Data)

Upstream product

• 143868-89-7 3-(1-oxopentyl)-4(S)-(phenylmethyl)-2-oxazolidinone 
• 882-33-7 diphenyldisulfane 
• 3561-67-9 bis(phenylthio)methane 
• 66275-60-3 1-Trimethylsiloxypent-1-ene 
• 833480-07-2 1,1-di(phenylthio)pentan-2-ol 
• 931-59-9 benzenesulfenyl chloride 
• 156546-61-1 (S)-4-Benzyl-3-((S)-2-phenylsulfanyl-pentanoyl)-oxazolidin-2-one 

Downstream Products

• 144015-76-9 (2R,3S,4S)-3-Hydroxy-2-methyl-4-phenylsulfanylheptan-1-ol 
• 143879-19-0 (2R,3S,4R)-3-Hydroxy-2-methyl-4-phenylsulfanylheptan-1-ol 

Relevant articles and documents

Synthesis of alkyl (α-phenylthioalkenyl) ketones containing a (Z)-trisubstituted olefinic fragment

Warren's method, which has been proposed for the synthesis of α-phenylthiodialkyl ketones, appeared to be inefficient for the preparation of their alkenyl alkyl analogs. The latter were prepared in good yields by alkenylation of alkyl phenylthiomethyl ketones with alkenyl bromides.

Kinetic resolution in asymmetric anti aldol reactions of branched and straight chain racemic 2-phenylsulfanyl aldehydes: Asymmetric synthesis of cyclic ethers and lactones by phenylsulfanyl migration

The kinetic resolution of branched and straight chain 2-phenylsulfanyl aldehydes by the Lewis acid-catalysed asymmetric anti aldol reaction followed by reduction to single enantiomers of 1,3-diols and/or acid-catalysed cyclisation with PhS migration provides a route to enantiomerically pure cyclic ethers and lactones with full stereochemical control.