143879-16-7

Basic information

• Product Name: (4S)-3-<(2R,3S,4R)-3-Hydroxy-2-methyl-4-phenylsulfanyl-1-oxohexyl>-4-(1-methylethyl)-1,3-oxazolidin-2-one
• Synonyms: (4S)-3-<(2R,3S,4R)-3-Hydroxy-2-methyl-4-phenylsulfanyl-1-oxohexyl>-4-(1-methylethyl)-1,3-oxazolidin-2-one
• CAS NO: 143879-16-7
• Molecular Weight: 365.494
• Mol File: 143879-16-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (4S)-3-<(2R,3S,4R)-3-Hydroxy-2-methyl-4-phenylsulfanyl-1-oxohexyl>-4-(1-methylethyl)-1,3-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4S)-3-<(2R,3S,4R)-3-Hydroxy-2-methyl-4-phenylsulfanyl-1-oxohexyl>-4-(1-methylethyl)-1,3-oxazolidin-2-one(143879-16-7)
• EPA Substance Registry System: (4S)-3-<(2R,3S,4R)-3-Hydroxy-2-methyl-4-phenylsulfanyl-1-oxohexyl>-4-(1-methylethyl)-1,3-oxazolidin-2-one(143879-16-7)

Safety Data

• Hazardous Substances Data: 143879-16-7(Hazardous Substances Data)

Upstream product

• 35874-97-6 α-(phenylthio)butanal 
• 77877-19-1 N-isopropyl oxazolidinone 

Downstream Products

• 17016-83-0 (4S)-4-isopropyl-1,3-oxazolidin-2-one 
• 182824-31-3 (2R,3S,4R)-3-Hydroxy-2-methyl-4-phenylsulfanylhexan-1-ol 

Relevant articles and documents

Kinetic resolution in asymmetric anti aldol reactions of branched and straight chain racemic 2-phenylsulfanyl aldehydes: Asymmetric synthesis of cyclic ethers and lactones by phenylsulfanyl migration

The kinetic resolution of branched and straight chain 2-phenylsulfanyl aldehydes by the Lewis acid-catalysed asymmetric anti aldol reaction followed by reduction to single enantiomers of 1,3-diols and/or acid-catalysed cyclisation with PhS migration provides a route to enantiomerically pure cyclic ethers and lactones with full stereochemical control.

Kinetic resolutions in anti aldol reactions with racemic 2-phenylthio aldehydes: Asymmetric synthesis of cyclic ethers and lactones with phenylthio migration

Kinetic resolutions in Lewis acid catalysed asymmetric anti aldol reactions of the boron enolate of imide (2) with racemic 2-phenylthio aldehydes (3a) - (3c) give good yields of anti,anti aldols (7). Synthesis of homochiral cyclic ethers (4a) - (4c) and (