35874-97-6

Basic information

• Product Name: Butanal, 2-(phenylthio)-
• CAS NO: 35874-97-6
• Molecular Formula: C10H12OS
• Molecular Weight: 180.271
• Mol File: 35874-97-6.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Butanal, 2-(phenylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanal, 2-(phenylthio)-(35874-97-6)
• EPA Substance Registry System: Butanal, 2-(phenylthio)-(35874-97-6)

Safety Data

• Hazardous Substances Data: 35874-97-6(Hazardous Substances Data)

Upstream product

• 23454-01-5 2,2-dichlorobutanal 
• 930-69-8 sodium thiophenolate 
• 24764-97-4 2-bromobutanal 
• 108-98-5 thiophenol 
• 156546-60-0 (S)-4-Benzyl-3-((S)-2-phenylsulfanyl-butyryl)-oxazolidin-2-one 
• 6651-33-8 1-(trimethylsiloxy)but-1-ene 
• 931-59-9 benzenesulfenyl chloride 
• 13884-92-9 phenylthiomethyl triphenylphosphonium chloride 
• 7205-91-6 phenylthiomethyl chloride 
• 882-33-7 diphenyldisulfane 
• 13865-50-4 methoxymethyl phenyl sulfide 
• 94633-75-7 1-Methoxy-1-phenylsulfanyl-butan-2-ol 
• 19980-22-4 Z-(1-buten-1-yloxy)trimethylsilane 
• 7182-10-7 N-(1-buten-1-yl)piperidine 

Downstream Products

• 120749-35-1 (2SR,3RS,4SR)-2,6-Dimethylphenyl 3-hydroxy-2-methyl-4-phenylsulfanylhexanoate 
• 140928-83-2 (2R^*,2'S^*,3S^*)-3,5-dimethyl-2-<1-(phenylthio)propyl>-2,3-dihydro-4H-pyran-4-one 
• 140928-84-3 (2R^*,2'S^*,3R^*)-3,5-dimethyl-2-<1-(phenylthio)propyl>-2,3-dihydro-4H-pyran-4-one 
• 143955-39-9 (4S)-3-<(2R,3S,4S)-3-Hydroxy-2-methyl-4-phenylsulfanyl-1-oxohexyl>-4-(1-methylethyl)-1,3-oxazolidin-2-one 
• 143879-16-7 (4S)-3-<(2R,3S,4R)-3-Hydroxy-2-methyl-4-phenylsulfanyl-1-oxohexyl>-4-(1-methylethyl)-1,3-oxazolidin-2-one 
• 140928-69-4 (2R^*,2'S^*)-2-<1-(phenylthio)propyl>-2,3-dihydro-4H-pyran-4-one 
• 140928-70-7 (2S^*,2'S^*)-2-<1-(phenylthio)propyl>-2,3-dihydro-4H-pyran-4-one 
• 57814-09-2 1-(phenylthio)-2-butanone 
• 77331-01-2 2-Chloro-2-phenylsulfanyl-butyraldehyde 
• 711028-69-2 (E)-5-Benzenesulfonyl-hept-3-en-2-one 
• 77331-04-5 2,2-bis(phenylthio)butanal 
• 35346-86-2 (Z)-2-Phenylsulfanyl-but-2-enal 

Relevant articles and documents

Reactivity of α-Halogenated Aldehydes towards Thiolates: Synthesis of α-Sulfenylated Aldehydes

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Stereochemical control in the synthesis of tetrahydrofurans by cyclisation of diols with [1,2]phenylsulfanyl migration

Acid catalysed rearrangement of a series of 4-PhS-1,3-diols with toluene-p-sulfonic acid in benzene gives stereospecifically substituted 3-PhS-tetrahydrofurans in excellent yield via a [1,2]-SPh shift. We comment on the structural variation at both the migration origin and terminus on the outcome of the title reaction and define its limits.

The synthesis of optically active 2-phenylthio aldehydes

Optically active linear and branched chain 2-phenylthio aldehydes can be made in high optical purity (up to > 98% e.e.) by sulfenylation of a phenylalanine-derivative oxazolidinone imide, reduction and re-oxidation with the Dess-Martin reagent even though the products enolise easily.