1443759-10-1

Basic information

• Product Name: 4-(3-chloro-benzoyl)-2,2-dimethyl-piperazine-1-carboxylic acid benzyl ester
• Synonyms: 4-(3-chloro-benzoyl)-2,2-dimethyl-piperazine-1-carboxylic acid benzyl ester
• CAS NO: 1443759-10-1
• Molecular Weight: 386.878
• Mol File: 1443759-10-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(3-chloro-benzoyl)-2,2-dimethyl-piperazine-1-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-chloro-benzoyl)-2,2-dimethyl-piperazine-1-carboxylic acid benzyl ester(1443759-10-1)
• EPA Substance Registry System: 4-(3-chloro-benzoyl)-2,2-dimethyl-piperazine-1-carboxylic acid benzyl ester(1443759-10-1)

Safety Data

• Hazardous Substances Data: 1443759-10-1(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 259808-67-8 3,3-dimethyl-piperazine-1-carboxylic acid tert-butyl ester 
• 1400761-07-0 2,2-dimethyl-piperazine-1,4-dicarboxylic acid 1-benzyl ester 4-tert-butyl ester 
• 1443758-97-1 2,2-dimethyl-piperazine-1-carboxylic acid benzyl ester trifluoroacetate 
• 618-46-2 m-Chlorobenzoyl chloride 

Downstream Products

• 1443757-61-6 [4-(3-chloro-benzoyl)-2,2-dimethyl-piperazin-1-yl]-(1-phenyl-1H-[1,2,4]-triazol-3-yl)-methanone 
• 1443759-11-2 (3-chloro-phenyl)-(3,3-dimethyl-piperazin-1-yl)-methanone trifluoroacetate 

Relevant articles and documents

PIPERAZINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLU5 RECEPTORS

This invention relates to compounds of formula (I) their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. R1, R2, R3, R4, Q have meanings given in the description.