144564-11-4 Usage
Description
(R)-tert-butyl 4-(4-chlorophenyl)-2-oxopyrrolidine-1-carboxylate is a chemical compound characterized by the molecular formula C15H19ClNO3. It is a pyrrolidine derivative featuring a tert-butyl group and a 4-chlorophenyl group attached to the pyrrolidine ring. (R)-tert-butyl 4-(4-chlorophenyl)-2-oxopyrrolidine-1-carboxylate is known for its unique chemical structure and properties, which make it a valuable asset in organic synthesis and pharmaceutical research.
Uses
Used in Pharmaceutical Research:
(R)-tert-butyl 4-(4-chlorophenyl)-2-oxopyrrolidine-1-carboxylate is utilized as a key building block in the synthesis of various biologically active compounds. Its application in this field is primarily due to its potential role in the development of new drugs, particularly those aimed at treating central nervous system disorders and other medical conditions.
Used in Organic Synthesis:
In the realm of organic synthesis, (R)-tert-butyl 4-(4-chlorophenyl)-2-oxopyrrolidine-1-carboxylate serves as an important intermediate. Its unique chemical structure allows it to be a versatile component in the creation of a wide range of compounds, contributing to the advancement of chemical research and development.
Other Industrial and Research Uses:
Owing to its distinctive chemical properties, (R)-tert-butyl 4-(4-chlorophenyl)-2-oxopyrrolidine-1-carboxylate may also find applications in other industries and research areas. While the specific uses may vary, the compound's potential for innovation and problem-solving in these fields is significant.
Check Digit Verification of cas no
The CAS Registry Mumber 144564-11-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,5,6 and 4 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 144564-11:
(8*1)+(7*4)+(6*4)+(5*5)+(4*6)+(3*4)+(2*1)+(1*1)=124
124 % 10 = 4
So 144564-11-4 is a valid CAS Registry Number.
144564-11-4Relevant articles and documents
Asymmetric synthesis of β-substituted γ-lactams via rhodium/diene-catalyzed 1,4-additions: Application to the synthesis of (R)-baclofen and (R)-rolipram
Shao, Cheng,Yu, Hong-Jie,Wu, Nuo-Yi,Tian, Ping,Wang, Rui,Feng, Chen-Guo,Lin, Guo-Qiang
supporting information; experimental part, p. 788 - 791 (2011/04/16)
An efficient rhodium/diene-catalyzed asymmetric addition of arylboronic acids to α,β-unsaturated γ-lactams has been developed. The power of this methodology is further demonstrated by the concise synthesis of (R)-baclofen and (R)-rolipram.
Stereospecific synthesis of (R)- and (S)-Baclofen and (R)- and (S)- PCPGABA [4-amino-2-(4-chlorophenyl)butyric acid] via (R)- and (S)-3-(4- chlorophenyl)pyrrolidines
Yoshifuji,Kaname
, p. 1302 - 1306 (2007/10/02)
(R)- and (S)-baclofen and (R)- and (S)-PCPGABA [4-amino-2-(4- chlorophenyl)butyric acid] were stereospecifically synthesized via (R)- and (S)-3-(4-chlorophenyl)pyrrolidines, starting from trans-4-hydroxy-L-proline. The syntheses involve two key operations
