1448450-28-9

Basic information

• Product Name: 2-(3,5-dimethylphenyl)-3-phenylisoquinolin-1(2H)-one
• Synonyms: 2-(3,5-dimethylphenyl)-3-phenylisoquinolin-1(2H)-one
• CAS NO: 1448450-28-9
• Molecular Weight: 325.41
• Mol File: 1448450-28-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(3,5-dimethylphenyl)-3-phenylisoquinolin-1(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,5-dimethylphenyl)-3-phenylisoquinolin-1(2H)-one(1448450-28-9)
• EPA Substance Registry System: 2-(3,5-dimethylphenyl)-3-phenylisoquinolin-1(2H)-one(1448450-28-9)

Safety Data

• Hazardous Substances Data: 1448450-28-9(Hazardous Substances Data)

Upstream product

• 609-67-6 2-Iodobenzoyl chloride 
• 88-67-5 2-Iodobenzoic acid 
• 333349-17-0 N-(3,5-dimethylphenyl)-2-iodobenzamide 
• 536-74-3 phenylacetylene 
• 13141-40-7 [2-(2-phenylethynyl)phenyl]methanol 
• 91000-43-0 3,5-dimethyl-N-benzylideneaniline 
• 29539-19-3 (Z)?1?benzylidene?1,3?dihydroisobenzofuran 

Relevant articles and documents

A simple access to N-(un)substituted isoquinolin-1(2H)-ones: Unusual formation of regioisomeric isoquinolin-1(4H)-ones

A ligand/additive/Pd-free Cu-mediated coupling/cyclization strategy afforded the first practical, one-pot and general approach towards synthesis of N-(un)substituted isoquinolin-1(2H)-ones. Both the catalyst and the solvent used are recyclable. The use of the Cu reagent in excess led to the unusual formation of regioisomeric and uncommon isoquinolin-1(4H)-ones. This journal is the Partner Organisations 2014.

Solvent-switched benzylic methylene functionalization: Addition, ring-opening, cyclization, and unexpected cleavage of C-O and C-C bonds

Intermolecular benzylic methylene functionalization of exo-cyclic enol ethers has been achieved using imines as reagents and potassium tert-butoxide as the catalyst. Depending on the solvent used, the reaction proceeds by two pathways. In THF, an addition