14489-76-0

Basic information

• Product Name: N-(naphthalen-1-ylmethyl)ethanamine
• Synonyms: 1-naphthalenemethanamine, N-ethyl-; ethyl(naphthalen-1-ylmethyl)amine; N-(1-Naphthylmethyl)ethanamine
• CAS NO: 14489-76-0
• Molecular Formula: C₁₃H₁₅N
• Molecular Weight: 185.2649
• Mol File: 14489-76-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 303.6°C at 760 mmHg
• Flash Point: 150.9°C
• Density: 1.019g/cm³
• Vapor Pressure: 0.000921mmHg at 25°C
• Refractive Index: 1.596
• PKA: 9.43±0.10(Predicted)
• CAS DataBase Reference: N-(naphthalen-1-ylmethyl)ethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(naphthalen-1-ylmethyl)ethanamine(14489-76-0)
• EPA Substance Registry System: N-(naphthalen-1-ylmethyl)ethanamine(14489-76-0)

Safety Data

• Hazardous Substances Data: 14489-76-0(Hazardous Substances Data)

Upstream product

• 75-04-7 ethylamine 
• 86-52-2 1-Chloromethylnaphthalene 
• 19351-91-8 N-(naphthalene-1-ylmethyl)acetamide 
• 5324-30-1 diethyl 2-bromoethylphosphonate 
• 118-31-0 (naphth-1-yl)methylamine 
• 19534-15-7 syn-1-<α-Naphthyl-propanon-(2)>-oxim 
• 19534-16-8 anti(α-Naphthyl)-1-α-naphthyl-propan-2-on-oxim-tosylat 
• 66-77-3 1-naphthaldehyde 

Downstream Products

• 318-87-6 ethyl-(2-fluoro-ethyl)-[1]naphthylmethyl-amine 
• 65503-09-5 (E)-N-ethyl-N-(3-phenyl-2-propenyl)-1-naphthalenemethanamine 

Relevant articles and documents

A novel fluorescent chemosensor for Cu(II) in aqueous solution based on a β-aminobisphosphonate receptor

A novel β-aminobisphosphonate receptor has been combined with naphthalene in the fluorophore-spacer-receptor format of a typical photoinduced electron transfer (PET) based sensor. The sensor was synthesised in two steps by first reacting aminomethylnaphth

Discovery of phosphoinositide 3-kinases (PI3K) p110β isoform inhibitor 4-[2-hydroxyethyl(1-naphthylmethyl)amino]-6-[(2S)-2-methylmorpholin-4-yl]-1H- pyrimidin-2-one, an effective antithrombotic agent without associated bleeding and insulin resistance

Structure-based evolution of the original fragment leads resulted in the identification of 4-[2-hydroxyethyl(1-naphthylmethyl)amino]-6-[(2S)-2- methylmorpholin-4-yl]-1H-pyrimidin-2-one, (S)-21, a potent, selective phosphoinositide 3-kinases (PI3K) p110β isoform inhibitor with favourable in vivo antiplatelet effect. Despite its antiplatelet action, (S)-21 did not significantly increase bleeding time in dogs. Additionally, due to its enhanced selectivity over p110α, (S)-21 did not induce any insulin resistance in rats.