145131-15-3 Usage
Urea derivative
Contains a urea functional group (NH2-C(O)-NH-C(O)-NH2)
The urea group is a common structural element in many pharmaceuticals and agrochemicals.
Cyclopentylmethylindole group
Contains a cyclopentyl and indole group connected through a methylene bridge
Cyclopentyl is a five-membered ring with a methyl group attached to it, and indole is a bicyclic aromatic compound with a benzene ring fused to a pyrrole ring.
Phenylurea group
Contains a phenyl group connected to the urea group
Phenyl is a benzene ring, and urea is a common structural element in many pharmaceuticals and agrochemicals.
Potential biological activity
May have biological effects and applications
The compound's structure suggests it could interact with biological targets, but further research is needed to determine its specific activities.
Medicinal and pharmaceutical research
Possible use in the development of new drugs or therapies
The compound's unique structure and potential biological activity make it a candidate for further investigation in the context of drug discovery.
Further investigation needed
Specific properties and potential applications require in-depth studies and experiments
To fully understand the compound's properties, potential applications, and mechanisms of action, additional research is necessary.
Check Digit Verification of cas no
The CAS Registry Mumber 145131-15-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,1,3 and 1 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 145131-15:
(8*1)+(7*4)+(6*5)+(5*1)+(4*3)+(3*1)+(2*1)+(1*5)=93
93 % 10 = 3
So 145131-15-3 is a valid CAS Registry Number.
145131-15-3Relevant articles and documents
New indole derivatives as ACAT inhibitors: Synthesis and structure-activity relationships
Bellemin,Decerprit,Festal
, p. 123 - 132 (2007/10/03)
A series of ureas containing the indole group were synthesized and assessed for their ability to inhibit arterial and intestinal ACAT and to lower plasma total cholesterol in a cholesterol-fed rat model. The structural modulations carried out in this series led to compounds which proved to be very active in both the inhibition of aortic ACAT in vitro and the inhibition of rat cholesterol intestinal absorption in vivo. Several compounds from this series exhibit a remarkable hypocholesterolaemic effect with ED25 less than 0.1 mg/kg po.