14521-80-3 Usage
Description
3-BROMO-1H-PYRAZOLE is an organic compound with the molecular formula C4H4BrN2. It is a heterocyclic compound featuring a pyrazole ring with a bromine atom at the 3-position. 3-BROMO-1H-PYRAZOLE is known for its reactivity and is widely utilized in the synthesis of various pharmaceuticals and agrochemicals due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
3-BROMO-1H-PYRAZOLE is used as a synthetic intermediate for the development of new pharmaceutical compounds. Its unique structure allows for the creation of a diverse range of molecules with potential therapeutic applications.
Used in Agrochemical Industry:
3-BROMO-1H-PYRAZOLE is used as a synthetic intermediate in the synthesis of Rynaxypyr (C325380), an insecticidal anthranilic diamide. Rynaxypyr acts as a potent and selective ryanodine receptor activator, making it an effective tool for pest control in agriculture. The compound targets specific receptors in insects, leading to paralysis and eventual death, thus providing a selective and environmentally friendly approach to pest management.
Check Digit Verification of cas no
The CAS Registry Mumber 14521-80-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,5,2 and 1 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 14521-80:
(7*1)+(6*4)+(5*5)+(4*2)+(3*1)+(2*8)+(1*0)=83
83 % 10 = 3
So 14521-80-3 is a valid CAS Registry Number.
InChI:InChI=1/C3H3BrN2/c4-3-1-2-5-6-3/h1-2H,(H,5,6)
14521-80-3Relevant articles and documents
METHODS FOR THE PREPARATION OF 5-BROMO-2-(3-CHLORO-PYRIDIN-2-YL)-2H-PYRAZOLE-3-CARBOXYLIC ACID
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Paragraph 0291-0296, (2021/04/23)
Described herein are novel methods of synthesizing 5-Bromo-2-(3-chloro-pyridin-2-yl)- 2H-pyrazole-3-carboxylic acid from pyrazole or pyrazole derivatives.
METHODS FOR THE PREPARATION OF 5-BROMO-2-(3-CHLORO-PYRIDIN-2-YL)-2H-PYRAZOLE-3-CARBOXYLIC ACID
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Paragraph 0194; 0195, (2021/04/23)
Described herein are novel methods of synthesizing 5-Bromo-2-(3-chloro-pyridin-2-yl)- 2H-pyrazole-3-carboxylic acid from pyrazole or pyrazole derivatives. Also described herein are novel reaction intermediates.
Strategy to Prepare 3-Bromo- and 3-Chloropyrazoles
Fox, Richard J.,Schmidt, Michael A.,Eastgate, Martin D.
, p. 2830 - 2839 (2018/03/09)
A general strategy to prepare substituted 3-bromo- and 3-chloropyrazoles is described. The three-step method involves condensation of crotonates or β-chloro carboxylic acids with hydrazines, followed by halogenation and oxidation. Several condensation and oxidation protocols were developed to enable preparation of a wide variety of 3-halopyrazoles with good to excellent yields and regiocontrol.
