145782-19-0

Basic information

• Product Name: N-(4-pentyn-1-yl)-4-methyl-benzenesulfonamide
• Synonyms: N-(4-pentyn-1-yl)-4-methyl-benzenesulfonamide
• CAS NO: 145782-19-0
• Molecular Weight: 237.323
• Mol File: 145782-19-0.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: N-(4-pentyn-1-yl)-4-methyl-benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-pentyn-1-yl)-4-methyl-benzenesulfonamide(145782-19-0)
• EPA Substance Registry System: N-(4-pentyn-1-yl)-4-methyl-benzenesulfonamide(145782-19-0)

Safety Data

• Hazardous Substances Data: 145782-19-0(Hazardous Substances Data)

Upstream product

• 70-55-3 toluene-4-sulfonamide 
• 3634-89-7 N-(p-toluenesulfonyl)aziridine 
• 106-96-7 propargyl bromide 
• 5390-04-5 pent-1-yn-5-ol 
• 18303-04-3 N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide 
• 68275-03-6 pent-4-yn-1-yl methanesulfonate 
• 19596-07-7 pent-4-ynenitrile 
• 309947-63-5 (N-tert-butoxycarbonyl)(pent-4-yn-1-yl)tosylamide 
• 15252-44-5 1-amino-pent-4-yne 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 145814-34-2 2-[1-Furan-2-yl-meth-(E)-ylidene]-1-(toluene-4-sulfonyl)-pyrrolidine 
• 145814-33-1 (E)-(2-thiophene-2-ylmethylene-pyrrolidine-1-yl)-p-tolylsulfone 
• 145782-25-8 2-[1-(Toluene-4-sulfonyl)-pyrrolidin-(2E)-ylidenemethyl]-pyridine 
• 145782-26-9 3-[1-(Toluene-4-sulfonyl)-pyrrolidin-(2E)-ylidenemethyl]-pyridine 
• 145782-24-7 2-[1-Phenyl-meth-(E)-ylidene]-1-(toluene-4-sulfonyl)-pyrrolidine 
• 145782-27-0 2-[2-Phenyl-prop-2-en-(E)-ylidene]-1-(toluene-4-sulfonyl)-pyrrolidine 
• 757998-08-6 4-methyl-N-(pent-3-yn-1-yl)benzenesulfonamide 
• 1088669-93-5 N-(6-hydroxy-8-phenyloct-4-yn-1-yl)-4-methylbenzenesulfonamide 
• 1088669-94-6 C₂₀H₂₉NO₅S 
• 145472-40-8 1-(toluene-4-sulfonyl)-piperidin-2-ol 
• 1282040-41-8 C₂₃H₂₇NO₂SSi 
• 1282040-39-4 C₂₀H₁₉NO₂S 
• 1282040-40-7 C₁₄H₁₅NO₂S 
• 1282040-16-7 C₂₄H₂₈N₂O₂SSi 

Relevant articles and documents

Gold(I)/Gold(III) Catalysis that Merges Oxidative Addition and π-Alkene Activation

Heteroarylation of alkenes with aryl iodides was efficiently achieved with a (MeDalphos)AuCl complex through AuI/AuIII catalysis. The possibility to combine oxidative addition of aryl iodides and π-activation of alkenes at gold is demonstrated for the first time. The reaction is robust and general (>30 examples including internal alkenes, 5-, 6-, and 7-membered rings). It is regioselective and leads exclusively to trans addition products. The (P,N) gold complex is most efficient with electron-rich aryl substrates, which are troublesome with alternative photoredox/oxidative approaches. In addition, it provides a very unusual switch in regioselectivity from 5-exo to 6-endo cyclization between the Z and E isomers of internal alkenols.

NaBArF4-Catalyzed Oxidative Cyclization of 1,5- and 1,6-Diynes: Efficient and Divergent Synthesis of Functionalized γ- and δ-Lactams

An efficient NaBArF4-catalyzed oxidative cyclization of readily available 1,5- and 1,6-diynes has been developed. Importantly, this transition metal-free oxidative catalysis proceeds via a presumable Lewis acid-catalyzed SN2’ pathway, which is distinct from the relevant oxidative rhodium and gold catalysis. This method leads to the facile and practical construction of a diverse range of synthetically useful γ- and δ-lactams in mostly good to excellent yields with broad substrate scope.

Synthesis of fused bicyclic aminals through sequential gold/Lewis acid catalysis

A novel sequential catalysis by combining gold catalysis with early transition metal catalysis was developed. Biologically important bicyclo[4.n.0] aminals were obtained under very mild conditions.