757998-08-6

Basic information

• Product Name: 4-methyl-N-(pent-3-yn-1-yl)benzenesulfonamide
• Synonyms: 4-methyl-N-(pent-3-yn-1-yl)benzenesulfonamide
• CAS NO: 757998-08-6
• Molecular Weight: 237.323
• Mol File: 757998-08-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-methyl-N-(pent-3-yn-1-yl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-N-(pent-3-yn-1-yl)benzenesulfonamide(757998-08-6)
• EPA Substance Registry System: 4-methyl-N-(pent-3-yn-1-yl)benzenesulfonamide(757998-08-6)

Safety Data

• Hazardous Substances Data: 757998-08-6(Hazardous Substances Data)

Upstream product

• 10229-10-4 pent-3-yn-1-ol 
• 14437-03-7 methyl tosylcarbamate 
• 18303-04-3 N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 15252-44-5 1-amino-pent-4-yne 
• 145782-19-0 N-(4-pentyn-1-yl)-4-methyl-benzenesulfonamide 
• 70-55-3 toluene-4-sulfonamide 
• 126745-57-1 C₁₇H₂₃NO₄S 

Downstream Products

• 73696-28-3 1-[(4-methylphenyl)sulfonyl]pyrrolidin-3-one 
• 1228437-96-4 C₁₈H₂₃NO₂S 
• 313666-12-5 N-ethynyl-4-methyl-N-pent-3-ynyl-benzenesulfonamide 
• 1218786-10-7 C₁₄H₁₉NO₂S 

Relevant articles and documents

Synthesis of Polysubstituted Fused Pyrroles by Gold-Catalyzed Cycloisomerization/1,2-Sulfonyl Migration of Yndiamides

Yndiamides (bis-N-substituted alkynes) are valuable precursors to azacycles. Here we report a cycloisomerization/1,2-sulfonyl migration of alkynyl-yndiamides to form tetrahydropyrrolopyrroles, unprecedented heterocyclic scaffolds that are relevant to medicinal chemistry. This functional group tolerant transformation can be achieved using Au(I) catalysis that proceeds at ambient temperature, and a thermally promoted process. The utility of the products is demonstrated by a range of reactions to functionalize the fused pyrrole core.

Rhodium-catalyzed carbonylative [3 + 2 + 1] cycloaddition of alkyne-tethered alkylidenecyclopropanes to phenols in the presence of carbon monoxide

A novel Rh-catalyzed carbonylative [3 + 2 + 1] cycloaddition of alkyne-tethered alkylidenecyclopropanes for the facile synthesis of bicyclic phenols in high yields has been developed. The reaction tolerated carbon and heteroatoms in the tether.