146667-95-0

Basic information

• Product Name: 2,2-dimethoxy-1-(4-methoxycarbonyl-2-nitrophenyl)ethane
• Synonyms: 2,2-dimethoxy-1-(4-methoxycarbonyl-2-nitrophenyl)ethane
• CAS NO: 146667-95-0
• Molecular Weight: 269.254
• Mol File: 146667-95-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2,2-dimethoxy-1-(4-methoxycarbonyl-2-nitrophenyl)ethane(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-dimethoxy-1-(4-methoxycarbonyl-2-nitrophenyl)ethane(146667-95-0)
• EPA Substance Registry System: 2,2-dimethoxy-1-(4-methoxycarbonyl-2-nitrophenyl)ethane(146667-95-0)

Safety Data

• Hazardous Substances Data: 146667-95-0(Hazardous Substances Data)

Upstream product

• 624-91-9 methyl nitrite 
• 126759-36-2 methyl 4-ethenyl-3-nitrobenzoate 
• 67-56-1 methanol 
• 104447-80-5 (E)-1-(dimethylamino)-2-[4-(methoxycarbonyl)-2-nitrophenyl]ethene 
• 96-98-0 4-methyl-3-nitrobenzoic acid 
• 133831-27-3 methyl 4-(2-(dimethylamino)vinyl)-3-nitrobenzoate 

Downstream Products

• 1204-32-6 methyl 1-methylindole-6-carboxylate 
• 182345-23-9 3-(1-Benzyl-piperidin-4-ylamino)-4-(2,2-dimethoxy-ethyl)-benzoic acid methyl ester 
• 1071216-81-3 3-(1-Benzyl-pyrrolidin-3-ylamino)-4-(2,2-dimethoxy-ethyl)-benzoic acid methyl ester 
• 182345-25-1 3-(1-Aza-bicyclo[2.2.2]oct-3-ylamino)-4-(2,2-dimethoxy-ethyl)-benzoic acid methyl ester 
• 182345-22-8 3-(1-Butyl-piperidin-4-ylamino)-4-(2,2-dimethoxy-ethyl)-benzoic acid methyl ester 
• 182345-24-0 4-(2,2-Dimethoxy-ethyl)-3-(1-ethyl-piperidin-3-ylamino)-benzoic acid methyl ester 
• 182345-21-7 4-(2,2-Dimethoxy-ethyl)-3-(1-methyl-piperidin-4-ylamino)-benzoic acid methyl ester 
• 1027993-17-4 3-(Cyclohexylmethyl-amino)-4-(2,2-dimethoxy-ethyl)-benzoic acid methyl ester 
• 1025901-98-7 4-(2,2-Dimethoxy-ethyl)-3-(1-ethyl-propylamino)-benzoic acid methyl ester 
• 167478-76-4 2-amino-4-carbomethoxy-phenylacetaldehyde dimethylacetal 
• 50820-65-0 indole-6-carboxylic acid methyl ester 

Relevant articles and documents

SUBSTITUTED BISINDOLYLMALEIMIDES FOR THE INHIBITION OF CELL PROLIFERATION

Compounds of the formula wherein R1, R1', R2, R2' R4, R5, R6 and R7 are as described herein; as well as pharmaceutically acceptable prodrugs or salts of acidic compounds of formula I with bases and or basic compounds of formula I with acids are antiprolif

Substituted pyrroles

Compounds of the formula STR1 wherein R 1 and R 1'' are independently alkyl, aryl, alkenyl or alkynyl;R 2 and R 2'' are independently hydrogen or alkyl;R 4, R 5, R 6 and R 7 each independently are STR2 CH 2 OR 10, CHO, CH 2 NR 11 R 12, hydrogen, halogen,

Palladium-Catalyzed Synthesis of Indoles from 2-Nitrostyrenes

In the presence of palladium salts, oxidation of 2-nitrostyrenes 1 with nitrous acid alkyl esters 2 resulted in the formation of 2-nitrophenylacetaldehyde dialkyl acetals 3.Reductive cyclization of the acetals 3 with iron powder in acetic acid afforded indoles 5 in good yield.